Results 221 to 230 of about 8,924,877 (409)

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

FEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno, Aki Terasaki, Yuiko Imai, Yuri Kimura, Yuna Kojima, Misa Irie, Koya Odaira, Mina Noura, Shuichi Okamoto, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa   +12 more
wiley   +1 more source

The effects of the human-like features of generative AI on usage intention and the moderating role of information overload. [PDF]

Sci Rep
Li X, Zhou T, Hu C, Liu H.
europepmc   +1 more source

Evaluation of the Topical Therapeutic Efficacy of Hexetidine (Sterisil) in Various Dermatoses

, 1958
ASHTON L. WELSH, Mitchell Ede
openalex   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Effect of family socio-economic status on subjective well-being among Norwegian adolescents: Mediation and moderation effects by general self-efficacy from a gendered perspective. [PDF]

BMC Public Health
Lorentzen CAN, Bauger L, Ambugo EA.
europepmc   +1 more source

ACADEMY OF SCIENCES. ON A NEW APPARATUS CAPABLE OF ACTING AS AN EXHAUSTING RECEIVER ON THE LOWER HALF OF THE BODY, WITH CASES ILLUSTRATIVE OF ITS EFFICACY [PDF]

M. Junod
openalex   +1 more source

Discussion of “The Efficacy of Floor Sills Under Drowned Hydraulic Jumps” [PDF]

, 1957
Serge Leliavsky
openalex   +1 more source

Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children

New England Journal of Medicine, 2018
A. Drilon, T. Laetsch, S. Kummar, S. DuBois, U. Lassen, G. Demetri, M. Nathenson, R. Doebele, A. Farago, A. Pappo, B. Turpin, A. Dowlati, M. Brose, L. Mascarenhas, N. Federman, J. Berlin, W. El-Deiry, C. Baik, J. Deeken, V. Boni, R. Nagasubramanian, Matthew H. Taylor, E. Rudzinski, F. Meric-Bernstam, D. Sohal, P. Ma, L. Raez, J. Hechtman, R. Benayed, M. Ladanyi, Brian B. Tuch, K. Ebata, S. Cruickshank, N. Ku, M. Cox, D. Hawkins, D. Hong, D. Hyman   +37 more
semanticscholar   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Effectiveness of the self-efficacy modification program for Thai alcoholic inpatients with schizophrenia. [PDF]

Discov Ment Health
Kiatsangorn T, Polngam D, Kaewarj N, Pilayon B, Phakdeekul W, Phoosuwan N.   +5 more
europepmc   +1 more source