Results 81 to 90 of about 8,614,944 (389)
Efficacy and safety of recombinant human activated protein C for severe sepsis.
New England Journal of Medicine, 2001 BACKGROUND Drotrecogin alfa (activated), or recombinant human activated protein C, has antithrombotic, antiinflammatory, and profibrinolytic properties.
G. R. Bernard +10 more
semanticscholar +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Journal of Ginseng Research, 2021 Background: Most clinical studies of immune responses activated by Korean Red Ginseng (KRG) have been conducted exclusively in patients. However, there is still a lack of clinical research on immune-boosting benefits of KRG for healthy persons.
Sun Hee Hyun +7 more
doaj
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Comparison of asthma phenotypes in OVA-induced mice challenged via inhaled and intranasal routes
BMC Pulmonary Medicine, 2019 Background The respiratory system is exposed to various allergens via inhaled and intranasal routes. Murine models of allergic lung disease have been developed to clarify the mechanisms underlying inflammatory responses and evaluate the efficacy of novel
Dong Im Kim, Mi-Kyung Song, Kyuhong Lee
doaj +1 more source
Collective efficacy belief, within-group agreement, and performance quality among instrumental chamber ensembles [PDF]
, 2018 We examined collective efficacy beliefs, including levels of within - group agreement and correlation with performance quality, of instrumental chamber ensembles (70 musicians, representing 18 ensembles).
Hendricks, Karin, Ray, James
core
Temporal adaptations in generic and population-specific quality of life and falls efficacy in men with recent lower-limb amputations [PDF]
, 2013 This study examined the longitudinal changes in generic health-related quality of life (QOL), prosthesis-related QOL, falls efficacy, and walking speed in men with lower-limb amputations up to 6 months following discharge from rehabilitation.
Barnett, CT, Polman, RCJ, Vanicek, N
core +2 more sources
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
Dispersant Efficacy and Effectiveness [PDF]
, 2011 Dispersants have been researched extensively and used for oil spill mitigation for more than 40 years, yet there are opportunities to enhance our understanding, including with respect to their long term fate and effects and how to optimize dispersant use.
Coolbaugh, Thomas, McElroy, Amy
core +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source