Results 91 to 100 of about 4,635,333 (255)

Optimization of Inorganic Ceramic Membrane Filtration Process for Tea Enzymes

Shipin gongye ke-ji
In order to enhance the clarity of tea enzymes while maximizing the preservation of their functional components during the clarification process, this experiment utilized tea enzymes derived from summer and autumn tea fermentation as the primary material.
Chunyan LI, Fuxiao WEI, Yu WANG, Chaoju ZHANG, Tiantian XU, Daoping WANG   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Innate Lymphoid Cells: Regulators of Gut Barrier Function and Immune Homeostasis

Journal of Immunology Research, 2019
Innate lymphoid cells (ILCs), identified in the early years of this century as a new class of leukocyte family unlike the B or T lymphocytes, play a unique role bridging the innate and adaptive immune responses in mucosal immunity.
Hui Fan, Aiyun Wang, Yuan Wang, Ye Sun, Jing Han, Wenxing Chen, Shijun Wang, Yuanyuan Wu, Yin Lu   +8 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Modulation of muscle anabolism and gut microbiota by Polyporus umbellatus extract attenuates dexamethasone-induced muscle atrophy

Applied Biological Chemistry
To investigate the pharmacological mechanisms by extract of Polyporus umbellatus (PU) protects against dexamethasone (DEX)-induced muscle atrophy, focusing on its direct effects on muscle cell signaling, mitochondrial function, oxidative stress, and its ...
Nguyen Bao Ngoc, Subeen Kim, Hye-Young Youn, Huitae Min, Tam Thi Le, Mauliasari Intan Rizki, Dae Won Kim, Kwang Hyeon Cha, Young Tae Park, Sang Hoon Jung, Myungsuk Kim   +10 more
doaj   +1 more source

Therapeutic Potential of Cinnamon Oil: Chemical Composition, Pharmacological Actions, and Applications

Pharmaceuticals
Cinnamon oil, an essential oil extracted from plants of the genus Cinnamomum, has been highly valued in ancient Chinese texts for its medicinal properties. This review summarizes the chemical composition, pharmacological actions, and various applications
Jiageng Guo, Xinya Jiang, Yu Tian, Shidu Yan, Jiaojiao Liu, Jinling Xie, Fan Zhang, Chun Yao, Erwei Hao   +8 more
doaj   +1 more source

Perceptions of Self-Efficacy for Inclusive Classroom Practices: a Survey of Italian EFL Teachers [PDF]

, 2023
openThe study aims at investigating the perceptions of self-efficacy for inclusive practices of Italian EFL teachers, given the fact that teachers' perceptions of self-efficacy appear to be related to a higher probability that they implement inclusive ...
ALFIERI, BEATRICE
core  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Heating conversion of indole-3-carbinol into N-substituted oligomers with anti-melanoma effect

Food Chemistry: X
Cruciferous vegetables (CVs) are globally consumed with some health benefits believed to arise from indole-3-carbinol (I3C), a labile phytochemical liberated from indole glucosinolates, but few reports describe the effect of cooking on I3C reactions ...
Jia Cheng Qian, Heng Peng Zhang, Yi Wang, Dan Liu   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source