Results 101 to 110 of about 4,486,711 (306)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

The role of Interpersonal Communication and Trust as antecedents of Organizational Citizenship Behavior (OCB)

Jurnal Maksipreneur: Manajemen, Koperasi, dan Entrepreneurship
Since Organizational Citizenship Behavior (OCB) has been found to be a factor that plays an important role in achieving organizational goals and employee work productivity, a lot of research has been conducted by scholars to show this.
Nancy Yusnita
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Entrepreneurial Orientation and Organizational Learning on SMEs' Innovation [PDF]

, 2015
Entrepreneurial orientation (EO) is a driver of firms’ innovation. The phenomenon of EO as a prerequisite for innovation has become a central focus of corporate entrepreneurship literature.
Wang, KY, Chelliah, J, Hermens, A, Huang, KP   +3 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Organizational tension between static and dynamic efficiency, The [PDF]

Efficiency has been defined in at least two different ways: in terms of the refinement of existing products, processes or capabilities (static efficiency) or the development of new ones (dynamic efficiency).
Ghemawat, Pankaj, Ricart, Joan E.
core  

Organizational downsizing [PDF]

, 1999
Plan BAlthough reports of job losses due to corporate restructuring are commonplace, close examination reveals that downsizing may not be the solution.
Kang, Hyun-gu
core  

Employees’ behavioral intention to use AI and organizational efficiency in an emerging economy: the serial mediating roles of technology readiness and digital culture

Discover Artificial Intelligence
The study leveraged the Technology-Organization-Environment theory to examine the serial mediation roles of technology readiness and digital culture of how employees’ behavioral intention to use AI influences organizational efficiency in an emerging ...
Hayford Asare Obeng, Bright Akwasi Gyamfi, Leviticus Mensah, Richard Arhinful, Abdullah Sarwar   +4 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Cooperative Organizational Strategies: A Neo-Institutional Digest [PDF]

This paper describes the neo-institutional approaches of transaction cost economics, agency theory, and property rights analysis and summarizes efforts by economists to apply these concepts to cooperatives.
Royer, Jeffrey S.
core