Results 91 to 100 of about 4,486,711 (306)

Organizational Form and Efficiency: An Analysis of Stock and Mutual Property-Liability Insurers [PDF]

open access: yes
This paper analyzes the efficiency of stock and mutual organizational forms in the property-liability insurance industry using nonparametric frontier efficiency methods.
J. David Cummins   +2 more
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

THE ROLE OF STRATEGIES FOR PREVENTION AND ADMINISTRATION OF ORGANIZATIONAL STRESS ON THE EFFICIENCY OF HUMAN RESOURCES [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2011
In knowledge-based organizations the stress becomes predictable and success ends up dependent on antistress organizational strategies, on the non-financial motivation and efficiency of human resource.
Mituţ Iulian
doaj  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Energy Efficiency Board 2017 programs and operations report.

open access: yes, 2018
Annual; Began with 2010; ceased with 2011.; At head of title: Connecticut Energy Efficiency ...
Connecticut. Energy Efficiency Board.
core  

National Action Plan for Energy Efficiency [PDF]

open access: yes, 2006
This report presents policy recommendations for creating a national commitment to energy efficiency through gas and electric utilities, utility regulators, and partner ...
National Action Plan for Energy Efficiency (U.S.)
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Organizational Institutions and Their Responsible Behavioral-Cultural Gene Codes and A Measurement for Organizational Efficiency [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2010
This essay has two goals. The first is to classify two different types of organizational institutions from the four-dimensional system-thinking perspective, and to identify the relationship between such organizational institutions and their relevant ...
Jason Jixuan
doaj  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

The impact of digital HRM system and digital transformation on HR efficiency with organizational agility as a moderator

open access: yesDiscover Sustainability
The study focuses on understanding the moderation effect of organizational agility in the impact of digital HRM system and digital transformation on HR efficiency in organizations intending to excel in the digital era. This study examines the association
Mo’men Hani Mahmoud   +4 more
doaj   +1 more source

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