Results 71 to 80 of about 114,747 (310)

The Impact of Leadership, Organizational Culture, And Organizational Structure on the Performance of the Finance Department at Aruna Senggigi Hotel

Indonesian Interdisciplinary Journal of Sharia Economics
Tourism is a vital economic sector, especially in destinations like Lombok, Known for its halal and sustainable tourism. Aruna Senggigi Hotel, one of the hotels implementing this concept, faces challenges in maintaining financial management efficiency ...
Lalu Imam Hardiansyah, Lalu Takdir Jumaidi   +1 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Managing the tensions of innovation and efficiency in the pursuit of organizational ambidexterity [PDF]

Whereas organizational ambidexterity is increasingly gaining ground in organizational theory, key issues regarding how ambidexterity is conceptualized, achieved and sustained offer partial insights or remain unexplored.
Papachroni, Angeliki
core  

Organizational Efficiency [PDF]

, 2021
openaire   +2 more sources

THE EFFICIENCY OF THE NETWORK ORGANIZATIONAL STRUCTURE OF COOPERATIVE BANKS

Journal of Financial Management, Markets and Institutions, 2023
The paper proposes an empirical investigation of scale economies, scope economies, and market power of the network organizational structure of Italian cooperative banks. For 452 cooperative banks (and a control group of 223 commercial banks) over 2006–2018, empirical findings show that cooperative banks experienced cost economies of scale and scope ...
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Control mechanisms and perceived organizational support: exploring the relationship between new and traditional forms of control

, 2014
Purpose: Taking into account the need to make a clearer distinction between traditional and new organizational controls, this paper aims to investigate similarities and differences between those two forms and explore the extent to which new forms of ...
Ofelia A. Palermo, Costa, T, Palermo, O., Costa, T., Palermo, OA, Duarte, H., Duarte, H, Tiago Costa, Henrique Duarte   +8 more
core   +1 more source

How Organizational Trust Affects the Market Position: The Mediating Role of Innovativeness and Operational Efficiency. Empirical Results [PDF]

, 2016
This study was conducted in 202 enterprises listed on the Warsaw Stock Exchange and provides documented evidence for a significant indirect impact of organizational trust on their market position through its effect on innovativeness and an improvement ...
Anna Sankowska, Sankowska, Anna
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source