Results 51 to 60 of about 71,692 (263)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

THE OUTSOURCING STRATEGIES FOR ORGANIZATIONAL EFFECTIVENESS AND EFFICIENCY

open access: yesJurnal Aplikasi Bisnis, 2006
Outsourcing is a management strategy by which an organization delegate major, non-core functions to specialized and efficient service providers. Outsourcing represents a significant shift in the way organizations manage and staff business support activities.
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The Impact of Organizational Change on Firm Performance—Analysis Based on SCM Modeling

open access: yesSAGE Open
Based on structural equation modeling, the impact of changes in organizational framework on firm performance and the intervention function of operational efficiency are scrutinized.
Lai Zhihuang, Zhang yuchen
doaj   +1 more source

A Meta-Analysis of Organizational Factors Effective of Efficiency and Motivation of Teachers [PDF]

open access: yesپژوهش در نظام‌های آموزشی, 2021
The data of the present research was initially collected by using research findings systematic review for the study of the organizational factors effective on teachers’ efficiency and motivation.
Zahra Hassani Abiz,   +3 more
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

From Organizational Culture to Efficiency in People Management: Development and Validation of the People Management Efficiency Scale (PMES)

open access: yesSocieties
This study investigates people management efficiency as a multidimensional organizational capability, contributing to the broader discussion on how organizational culture and internal processes are associated with management effectiveness as a socially ...
Susana Ribeiro, Rosa Isabel Rodrigues
doaj   +1 more source

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