Results 41 to 50 of about 9,268,102 (350)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A comparative study in organizational culture between the administrative and technical staffs of the participating teams in the West Asian Taekwondo Championship [PDF]

open access: yesمجلة الرافدين للعلوم الرياضية, 2013
The research aims to identify the organizational culture of the Angels and administrative technical staffs for teams participating in the West Asian Taekwondo Championship, and the difference in organizational culture between the administrative staffs of
Waleed Ragab   +2 more
doaj   +1 more source

Methodology of Estimation of Parameters in the Mechanism of Selecting Organizational and Technological Solutions

open access: yesNauka ta progres transportu, 2021
Purpose. The aim of this study is the substantiation of the methodology for assessing the choice parameters of the organizational and technological solutions, the selection mechanism is based on and determining the expediency of a particular decision ...
A. A Ichetovkin
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Organizational Performance and its Affect on Job Satisfaction

open access: yesJournal of Business and Social Review in Emerging Economies, 2020
This paper aims to find the existing relationship between organizational performance and its effect on the level of job satisfaction. However, given the importance of employee satisfaction on corporate performance, many companies do not pay due attention
Najma Sadiq   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

An empirical study on the relationship between effective organizational communication and the performance of central office staff [PDF]

open access: yesManagement Science Letters, 2012
Inter-organizational communication plays an important role in promoting strategic collaboration among firms. It can improve productivity and increases collaboration among employees.
Abbas Monavvarian, Golnaz Mehdi Asri
doaj  

Domestic Outsourcing, Rent Seeking, and Increasing Inequality [PDF]

open access: yes, 2017
An increasing share of the economy is organized around financial capitalism, where, in contrast to the past, capital market actors actively assert and manage their claims on wealth creation and distribution.
Eileen Appelbaum
core   +1 more source

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