Results 31 to 40 of about 114,747 (310)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
, 2018 Objective: This work aims to systematize and contextualize relevant theoretical and practical considerations in the dynamics of talent management in a business context, as well as observe in the practical implementation in small and medium enterprises in
Pereira, Manuel
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The nexus among perceived organizational support, organizational justice and cynicism
, 2021 Purpose - A traditional view of an ideal workplace is an organization with a justice climate and a supportive atmosphere. Over the past years, justice and support practices in the workplace have received significant scholarly, practical and even ...
Mert, İbrahim Sani +2 more
core +1 more source
An empirical study on the relationship between effective organizational communication and the performance of central office staff [PDF]
Management Science Letters, 2012 Inter-organizational communication plays an important role in promoting strategic collaboration among firms. It can improve productivity and increases collaboration among employees.
Abbas Monavvarian, Golnaz Mehdi Asri
doaj
Organizational DNA as a Mediating Variable in the Relationship Between Knowledge Management and Outstanding Performance: An Application to Egyptian Public Banks [PDF]
المجلة العلمية للدراسات والبحوث المالية والتجاريةPurpose – This research seeks to analyze the direct impact of Knowledge Management on Organizational DNA, examine the influence of Organizational DNA on Outstanding Performance, and determine the extent to which Organizational DNA serves as a mediating ...
Ibrahim Reda Ibrahim Helal +1 more
doaj +1 more source
Organizational Performance and its Affect on Job Satisfaction
Journal of Business and Social Review in Emerging Economies, 2020 This paper aims to find the existing relationship between organizational performance and its effect on the level of job satisfaction. However, given the importance of employee satisfaction on corporate performance, many companies do not pay due attention
Najma Sadiq +3 more
doaj +1 more source