Results 131 to 140 of about 13,947,017 (382)

A STUDY IN EFFICIENCY [PDF]

open access: yesSchool Science and Mathematics, 1910
n ...
openaire   +3 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Introducing Energy Efficiency into SQALE [PDF]

open access: yes, 2013
Energy Efficiency is becoming a key factor in software development, given the sharp growth of IT systems and their impact on worldwide energy consumption.
Ardito, Luca   +3 more
core  

EFFICIENCY IN NURSING [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1913
This title is intended to describe the much-neglected field of the economic side of ward nursing, especially in the larger hospitals. Recent magazines are filled with articles discussing "efficiency" in laying bricks or handling tools, and "get-together" principles are the order of the day, but one looks in vain for any serious discussion of the ...
openaire   +2 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Elucidating the Role of Transcriptomic Networks and DNA Methylation in Collagen Deposition of Dezhou Donkey Skin

open access: yesAnimals
DNA methylation represents a predominant epigenetic modification with broad implications in various biological functions. Its role is particularly significant in the process of collagen deposition, a fundamental aspect of dermal development in donkeys ...
Xinrui Wang   +11 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

How Does Financial Reporting Quality Relate to Investment Efficiency?

open access: yes, 2009
Prior evidence that higher-quality financial reporting improves capital investment efficiency leaves unaddressed whether it reduces over- or under-investment.
Gary C. Biddle   +2 more
semanticscholar   +1 more source

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