Results 131 to 140 of about 2,645,492 (268)

Coordinating production-living-ecological space efficiency in suburban rural areas using a DEA-triangular model. [PDF]

iScience
Zhao T, Xu W, Cheng Y, Yuan R, Fan Y.
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Comparative efficiency of Asian surgical systems in COVID-19 response: a multi-level longitudinal benchmarking study. [PDF]

BMJ Public Health
Lam SSW, Kumar A, Ge Y, Chan SL, Pourghaderi AR, Zaw MWW, Khan AZ, Roslani ACC, Selvakumaran C, Jarmin R, Ngoc DH, Sari DK, Dey D, Nguyen Thi-Ngoc D, Dao DT, Nguyen Vu Minh D, Raduan F, Son GV, Le H, Lubis IND, Khalid K, Nawawi K, Kit KJ, Meetei LT, Fatima M, Fahdy M, Ichwan M, Sinam N, Nepram SS, Kania N, Goswami N, Borah NC, Nurikhwan PW, Phang MY, Sarkar P, Bui DT, Do Pham Nguyet T, Nguyen VT, Tran QV, Chen Z, Rao V, Chow PKH, Tan HK.   +42 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Verbal and Visuospatial Working Memory Performance During the CO₂ Challenge Model of Anxiety. [PDF]

Hum Psychopharmacol
Dunger W, Edwards M, Board A, Garner M.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Dynamic changes and heterogeneity in technical efficiency of broiler production under African swine fever shocks: Evidence from production organization and farm size. [PDF]

Poult Sci
Guo D, Zhuo X, Pu H.
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Design and Experimental Analysis of a Multi-Scale Fresh Tea Leaf Rotary Drum Screen Based on the DEM-RSM Method. [PDF]

Food Sci Nutr
Zhang X, Wang R, Zhou Z.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source