Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
THE BIOLOGICAL EFFICIENCY OF POTATO NITROGEN
Mary Swartz Rose, Lenna F. Cooper
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Dust Retention Efficiencies of Dustfall Collectors [PDF]
John S. Nader
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Research on policy effect and regional difference of allocation efficiency of rural preschool education resources: evidence from China. [PDF]
Tang MM, Lan Q.
europepmc +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
LABORATORY AND PLANT: A RAPID METHOD FOR COMPARING THE DECOLORIZING EFFICIENCY OF CHARCOALS [PDF]
Leonard. Wickenden, John W. Hassler
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Investigating the efficiency of medical and health resources and its influencing factors in the Yangtze River Delta urban agglomerations: based on the undesirable super-efficiency SBM-Malmquist-Tobit model. [PDF]
Chen Y, Li Q, Zhang Y, Zhang X, Zheng H.
europepmc +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source