Results 71 to 80 of about 9,727,327 (310)

Nucleosomes affect local transformation efficiency [PDF]

open access: yes, 2012
Genetic transformation is a natural process during which foreign DNA enters a cell and integrates into the genome. Apart from its relevance for horizontal gene transfer in nature, transformation is also the cornerstone of today's recombinant gene ...
Aslankoohi, Elham   +6 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Photoinhibiting via simultaneous photoabsorption and free-radical reaction for high-fidelity light-based bioprinting

open access: yesNature Communications, 2023
Light-based 3D bioprinting is now employed widely to fabricate geometrically complex constructs for various biomedical applications. However, the inherent light scattering defect creates significant challenges in patterning dilute hydrogels to form high ...
Ning He   +11 more
doaj   +1 more source

Thermodynamic Efficiency in Dissipative Chemistry [PDF]

open access: yes, 2019
Chemical processes in closed systems are poorly controllable since they always relax to equilibrium. Living systems avoid this fate and give rise to a much richer diversity of phenomena by operating under nonequilibrium conditions.
Esposito, Massimiliano   +2 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

On the energy efficiency-spectral efficiency trade-off in the uplink of CoMP system [PDF]

open access: yes, 2012
In this paper, we derive a generic closed-form approximation (CFA) of the energy efficiency-spectral efficiency (EE-SE) trade-off for the uplink of coordinated multi-point (CoMP) system and demonstrate its accuracy for both idealistic and realistic power
Héliot, Fabien   +2 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Does search boost efficiency? [PDF]

open access: yes, 2015
Poaching externality, arising from job-to-job turnovers, implies that a planner should allocate fewer resources to costly job creations. However, these search efforts increase competition among employers, and this could in turn internalize the ...
Ge, Teng
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Increasing the Wear Resistance of CrWMn Tool Steel Surfaces by Plasma Electrolytic Nitriding and Polishing

open access: yesApplied Sciences
The positive effect of plasma electrolytic treatment on CrWMn tool steel to increase the wear resistance of its surface is shown. The effect of plasma electrolytic nitriding and subsequent polishing on the structure, phase and elemental composition ...
Sergey N. Grigoriev   +8 more
doaj   +1 more source

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