Results 131 to 140 of about 368,658 (306)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Performance analysis for network coding using ant colony routing

open access: yes, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The aim of this thesis is to conduct performance investigation of a combined system of Network Coding (NC) technique with Ant-Colony (ACO) routing protocol.
Sabri, Dalia
core  

Calculus of service guarantees for network coding [PDF]

open access: yes, 2006
A large class of networks is able to provide some guarantees in terms of quality of service, end-to-end delays and throughput to data flows. In return, the data flows must verify constraints of burstiness and throughput.
Fraboul, Christian   +2 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Distributed video coding in wireless multimedia sensor network for multimedia broadcasting

open access: yes, 2008
Recently the development of Distributed Video Coding (DVC) has provided the promising theory support to realize the infrastructure of Wireless Multimedia Sensor Network (WMSN), which composed of autonomous hardware for capturing and transmission of ...
Zhuo, X, Loo, KK, Cosmas, J, Yip, PY
core  

Efficient value synthesis in the orbitofrontal cortex explains how loss aversion adapts to the ranges of gain and loss prospects

open access: yeseLife
Is irrational behavior the incidental outcome of biological constraints imposed on neural information processing? In this work, we consider the paradigmatic case of gamble decisions, where gamble values integrate prospective gains and losses.
Jules Brochard, Jean Daunizeau
doaj   +1 more source

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