Results 141 to 150 of about 368,658 (306)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Transform coding of compound images using matching pursuit

open access: yes, 2012
Mixed Raster Content (MRC) coding is an efficient way of coding compound images. The layered model used gives rise to missing data in the foreground and background layers. When using a block-based transform for coding, the usual solution has been to fill
H. Nautsch   +3 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Efficient coding of natural scenes improves neural system identification. [PDF]

open access: yesPLoS Comput Biol, 2023
Qiu Y   +8 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

A Comparison of Image Statistics of Peacock Jumping Spider Colour Patterns and Natural Scenes

open access: yesEcology and Evolution
The form of arbitrary sexual signals may be driven by the need to be detectable against the background or, alternatively, by selection for efficient processing by the nervous system. This latter alternative is a prediction of the sensory drive hypothesis
Marie‐Christin Hardenbicker   +2 more
doaj   +1 more source

Efficient coding, channel capacity, and the emergence of retinal mosaics. [PDF]

open access: yesAdv Neural Inf Process Syst, 2022
Jun NY, Field GD, Pearson JM.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

An efficient method for data exchange using network coding and narrowband multiuser detection

open access: yes, 2011
The proposed technique applies to full duplex mobile-to-mobile pair wise communication via a common centralized node such as a base station or satellite.
Aghvami, A.H.   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy