Results 81 to 90 of about 368,658 (306)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Correlated activity supports efficient cortical processing

open access: yesFrontiers in Computational Neuroscience, 2015
Visual recognition is a computational challenge that is thought to occur via efficient coding. An important concept is sparseness, a measure of coding efficiency.
Chou Po Hung   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Network Coding with Limited Overhearing [PDF]

open access: yes, 2011
The two key benefits of network coding are increased reliability and throughput. Most network coding approaches for wireless networks rely on overhearing neighboring transmissions. Overhearing in sensor networks, however, is not energy-efficient. In this
Samarasinghe, Kasun   +3 more
core  

T-type calcium channels promote predictive homeostasis of input-output relations in thalamocortical neurons of lateral geniculate nucleus

open access: yesFrontiers in Computational Neuroscience, 2014
A general theory views the function of all neurons as prediction, and one component of this theory is that of predictive homeostasis or prediction error.
Su Z. Hong   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Distributed Source-coding, Channel-coding and Modulation for Cooperative Communications [PDF]

open access: yes, 2010
In this contribution, we propose a novel Distributed Source-coding, Channel-coding and Modulation (DSCM) scheme for cooperative communications. The proposed DSCM scheme is designed for ensuring the decoding convergence of its constituent component codes,
Ng, Soon   +5 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Block-Run Run-Length Coding of Handwriting and Bilevel Graphics Based on Quadtree Segmentation

open access: yes, 1997
An efficient off-line coding scheme for handwriting and bilevel graphics based on quadtree segmentation and block-run run-length coding (RLC) is presented.
Yuen, H, Hanzo, L
core  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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