Results 121 to 130 of about 2,813,925 (355)

Energy efficiency of consecutive fragmentation processes

open access: yes, 2010
We present a first study on the energy required to reduce a unit mass fragment by consecutively using several devices, as it happens in the mining industry.
Bertoin   +5 more
core   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Considerations on the factors that limit the management of energy efficiency in the organizations of Santiago de Cuba

open access: yesSantiago, 2017
The work aims to argue from the factors; Political, economic and cultural importance of promoting the efficient use of energy resources in the organization, in order to promote the development of a culture in favor of the efficient use of these resources.
Mónica Rosario Berenguer-Ungaro   +3 more
doaj  

Energy Efficient and Secure Information Dissemination in Heterogeneous Wireless Sensor Networks Using Machine Learning Techniques [PDF]

open access: hybrid, 2022
Deepak Dudeja   +6 more
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Energy efficiency in small and medium scale foundry industry

open access: yesMetalurgija, 2016
In this paper, the research results of surveys which were conducted in an Indian foundry cluster which are potential members of such sectors are presented. These results indicate that there is an enough potential improvement in the energy use. The use of
G. Patange, M. Khond
doaj  

Minimum free-energy path of homogenous nucleation from the phase-field equation

open access: yes, 2009
The minimum free-energy path (MFEP) is the most probable route of the nucleation process on the multidimensional free-energy surface. In this study, the phase-field equation is used as a mathematical tool to deduce the minimum free-energy path (MFEP) of ...
Christian J. W.   +3 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Energy-use efficiency of organic and conventional plant production systems in Germany

open access: yesScientific Reports
Sustainable and efficient energy use in agriculture helps tackle climate change by reducing fossil energy use. We evaluated German farming systems by analysing energy input and output.
Lucie Chmelíková   +3 more
doaj   +1 more source

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