Results 111 to 120 of about 2,836,622 (305)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Hot-electron transfer in quantum-dot heterojunction films
Nature Communications, 2018 Efficient use of high-energy, or “hot”, carriers could increase the efficiency of solar cells, provided efficient extraction of electrons at a specific energy.
Gianluca Grimaldi +11 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Santiago, 2017 The work aims to argue from the factors; Political, economic and cultural importance of promoting the efficient use of energy resources in the organization, in order to promote the development of a culture in favor of the efficient use of these resources.
Mónica Rosario Berenguer-Ungaro +3 more
doaj
Spatial Development and Energy Consumption [PDF]
Previous literature has suggested that the urban form (i.e., city size, density, and center distribution pattern) influences urban energy consumption.
Harrington, Winston +2 more
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The Use of Contact Heat Generators of the New Generation for Heat Production [PDF]
, 2016 We substantiated the need for searching for, and realization of, fundamentally new approaches, using more efficient physical, heat-mass-exchanging and aerodynamic processes, which will make it possible to improve energy effectiveness and ecological ...
Daschenko, O. (Olga) +4 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Options for Energy Efficiency in India and Barriers to Their Adoption: A Scoping Study [PDF]
We review the economics literature on energy efficiency in India, as a guide for further research in the area. The empirical literature has focused on four questions: How does energy efficiency in India compare with energy efficiency in other countries ...
Bhattacharya, Soma, Cropper, Maureen L.
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The use of social media for improving energy consumption awareness and efficiency: An overview of existing tools [PDF]
, 2015 Raising consumers’ awareness of energy consumption is one of the first steps in encouraging the adoption of energy saving behaviours that result in energy efficiency.
Fragidis, G +4 more
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