Results 121 to 130 of about 2,836,622 (305)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Energy efficiency in small and medium scale foundry industry
Metalurgija, 2016 In this paper, the research results of surveys which were conducted in an Indian foundry cluster which are potential members of such sectors are presented. These results indicate that there is an enough potential improvement in the energy use. The use of
G. Patange, M. Khond
doaj
Energy-use efficiency of organic and conventional plant production systems in Germany
Scientific ReportsSustainable and efficient energy use in agriculture helps tackle climate change by reducing fossil energy use. We evaluated German farming systems by analysing energy input and output.
Lucie Chmelíková +3 more
doaj +1 more source
Energy Use Efficiency in Biomass Production Systems [PDF]
, 2005 Fossil energy use efficiency is higher in low-input crop production systems than in high-input systems. This is caused by the fact that in low-input systems, a relatively large amount of the used nitrogen originates from non-fossil resources. In energy crop production systems, solar energy is converted into plant material (with the aid of fossil energy)
openaire +2 more sources
Organic farming and resource efficiency [PDF]
, 2011 The Chapter discusses the efficiency of nutrient and energy use in organic farming, regarding the pressing need to make efficient use of natural resources.
de Neergaard, Andreas, Oelofse, Myles
core
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source