Results 171 to 180 of about 67,098 (243)

Ammonification Process Is Limited by Transformation of Medium Molecular Weight Nitrogenous Organics but Not Hydrolysis of Proteins

Advanced Science, EarlyView.
A multi‐level analytical framework, integrating protein‐level persistence analysis, nontargeted HRMS formula tracking, peptide‐level proteomics, and targeted monomer quantification under varying redox conditions, together with FMO calculations reveal that ammonification is limited by medium molecular weight nitrogenous multimers.
Jing Li, Junjie Qiu, Fan Lü, Hua Zhang, Pinjing He   +4 more
wiley   +1 more source

Platycodon grandiflorus–Derived Nanovesicles Sensitize Gastric Cancer to T Cell Killing via Ferroptosis‐Driven Membrane Mechanical Remodeling

Advanced Science, EarlyView.
Plant‐derived nanovesicles from Platycodon grandiflorus act as bioactive lipid delivery platforms that transport γ‐linolenic acid into gastric cancer cells. This lipid cargo promotes ferroptotic lipid peroxidation, remodels membrane mechanics, and increases tumor‐cell susceptibility to cytotoxic T‐cell attack.
Jian Wu, Ruijuan Zhang, Yixin Duan, Shuqi Huo, Xiang Zhang, Yibin Xing, Lingjing Ma, Tiran Jiang, Xingyu Chen, Qingmin Sun   +9 more
wiley   +1 more source

Experiments on Nonlocal Fluid‐Flow Metamaterials

Advanced Science, EarlyView.
A nonlocal fluid‐flow metamaterial composed of standard microfluidic tubes and connectors is designed. Hence, the current of the system at one position depends on the gradient of fluid flow at many other positions, leading to unusual alternating backward and forward laminar flows of water.
Ke Wang, Yi Chen, Martin Wegener
wiley   +1 more source

Unlocking Zenith Electronic State of Ni Sites in Ligand‐Engineered COFs for Efficient •O2−‐Driven Uranium Photoreduction

Advanced Science, EarlyView.
We develop a ligand engineering strategy to construct Ni‐diketimine‐linked COFs with precisely tuned Ni electronic states. By varying the coordinated diketone units, we achieve an optimal electronic configuration that enhances O2 adsorption and lowers the energy barrier for •O2− generation.
Guihong Wu, Fengtao Yu, Lin Wen, Sai‐Jin Xiao, Fangru Song, Jian‐Ding Qiu   +5 more
wiley   +1 more source

Thermal Shifts Dominate Single‐Gene Responses to Transcription‐Targeting Antibiotics

Advanced Science, EarlyView.
Thermal shifts reshape bacterial responses to transcription‐targeting antibiotics. In E. coli, temperature can dominate antibiotic‐induced genome‐wide expression, particularly outside 30°C–39°C, through changes in adenosine triphosphate (ATP), nucleoid organization, and drug‐target engagement.
Rahul Jagadeesan, Amir M. Arsh, Vatsala Chauhan, Suchintak Dash, Pooja Ravaria, Andre S. Ribeiro   +5 more
wiley   +1 more source

Multifunctional Ionic Liquid Enabling Cation Homogenization and Lead Chelation for Pure‐Iodide Wide‐Bandgap Perovskite Solar Cells

Advanced Science, EarlyView.
This work presents a multifunctional ionic liquid, [SO3H‐PMIm][OTf], that addresses A‐site cation inhomogeneity and lead toxicity in pure‐iodide wide‐bandgap perovskite solar cells. The additive enables homogeneous cation distribution, achieving 22.02% efficiency with 90% retention after 3000 h and reducing lead leakage by over 58%, thereby ...
Kai Wu, Lei Yang, Guoqing Du, Xin Wang, Jiali Wei, Tiantian Li, Pengfei Zhang, Xiaodan Zhang, Fuhua Hou   +8 more
wiley   +1 more source

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

Advanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang, Lun Zhu, Ze Sun, Ruolin Jia, Ziming Wang, Jiayao Zhao, Bohao Liu, Haiqing Xiong, Xiaowei Yu, Yanzhu Yue   +9 more
wiley   +1 more source

Atomically Dispersed Fe‐Modified SnS for Sn‐Centered Peroxymonosulfate Activation Toward Acetaminophen Degradation

Advanced Science, EarlyView.
Atomically dispersed Fe regulates the local electronic environment and surface properties of SnS, while PMS preferentially coordinates to Sn through Sn–O interaction. Fe incorporation further enhances the Sn–OPMS interfacial interaction, facilitating Sn‐centered PMS activation and the generation of SO4•−/•OH for APAP degradation, thereby clarifying the
Shuhui Liu, Yantao Wang, Ya Liu, Jingkai Lin, Shaobin Wang, Wenjie Tian   +5 more
wiley   +1 more source

Long‐Term Human Skin Platform for Modeling Chronic Inflammation, Environmental Stress, and Therapeutic Intervention

Advanced Science, EarlyView.
An advanced, long‐term human skin platform maintains native skin structure and key tissue functions for up to four weeks. The platform models chronic inflammation, aging‐related skin changes, and UVB damage, enabling drug and topical interventions—including anti‐inflammatory therapy, senolytic treatment, and sunscreen—to be evaluated in intact human ...
Purnendu Kumar Sharma, Evelien Schaafsma, Elysia Anderson, Jocelyn Chiari, Paige Thompson, Erin Galt, Sunghoon Lee, Jason Holsapple, Sai Hein, Bailey L. Coates, Jade Michaud, Sabrina Zuccaro, Lia Kent, Chris Hinojosa, Kyung‐Jin Jang   +14 more
wiley   +1 more source

Self‐Healing Pd(II) Cage Metallogels for Iodine Capture in Water and Heterogeneous Photocatalysis

Advanced Science, EarlyView.
Two carbazole‐derived metal‐organic cages hierarchically self‐assemble into supramolecular metallogels that integrate autonomous self‐healing, reversible stimuli responsiveness, high‐capacity aqueous iodine capture, and visible‐light‐driven photocatalytic sulfide oxidation within a single multifunctional platform.
Monotosh Dalapati, Raghunath Singha, Debashree Manna, Dipak Samanta   +3 more
wiley   +1 more source