Results 311 to 320 of about 427,575 (339)
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Clinica Chimica Acta, 1973
Abstract Evidence is presented to suggest that enzyme protein retention in the cell depends on adequate adenosine triphosphate (ATP), and the behaviour of erythrocytes seems to support this. Further evidence suggests that retention is mediated within the cell and not simply by the cell membrane, which appears permeable to enzyme molecules.
J C, Sweetin, W H, Thomson
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Abstract Evidence is presented to suggest that enzyme protein retention in the cell depends on adequate adenosine triphosphate (ATP), and the behaviour of erythrocytes seems to support this. Further evidence suggests that retention is mediated within the cell and not simply by the cell membrane, which appears permeable to enzyme molecules.
J C, Sweetin, W H, Thomson
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Quantifying Cellular Cholesterol Efflux
2019Measuring cholesterol efflux involves the tracking of cholesterol movement out of cells. Cholesterol efflux is an essential mechanism to maintain cellular cholesterol homeostasis, and this process is largely regulated via the LXR transcription factors and their regulated genes, the ATP-binding cassette (ABC) cholesterol transporters ABCA1 and ABCG1 ...
Sabrina, Robichaud, Mireille, Ouimet
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Bacterial Efflux Pump Inhibitors
2008Infections caused by multidrug-resistant Gram-negative pathogens play a major role in the morbidity and mortality of hospitalized patients. The rise of resistance to current antibiotic therapies has made the discovery of new agents urgent. One of the major antibiotic resistance mechanisms utilized by more than 15 species of Gram-negative bacterial ...
Barbara J, Kamicker +7 more
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Microbial Efflux of Antibiotics and Inhibitors of Efflux Pumps
2014Detergent-like bile salts kill bacterial cells by destroying bacterial multidrug resistance (MDR) efflux systems. These not only play an important role in antibacterial resistance but also contribute to bacterial pathogenesis. Reserpine and H+/K+ ATPase inhibitors can significantly reduce MICs, increase killing activity, and prolong the postantibiotic ...
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