Results 141 to 150 of about 173,318 (310)
The Mechanism of Vertical Fiscal Imbalance Affecting High-Quality Economic Development : A 3SLS Estimation Based on Local Government Tax Effort and Expenditure Structure. [PDF]
Against the backdrop of China’s transition toward high-quality economic development, it is imperative to explore the mechanisms through which the fiscal system influences development quality.
Venus Liew, Khim Sen, Ke, Wang
core +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Supporting Effort Estimation in Agile Software Development
, 2015 Background: In Agile Software Development (ASD) planning is valued more than the resulting plans. Planning and estimation are carried out at multiple levels in ASD. Agile plans and estimates are frequently updated to reflect the current situation.
Usman, Muhammad
core
Software Development Effort Estimation Using Regression Fuzzy Models. [PDF]
Comput Intell Neurosci, 2019 Nassif AB, Azzeh M, Idri A, Abran A.
europepmc +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Use case estimation - the devil is in the detail
, 2004 Mission critical and complex software projects habitually exceed budget expectations significantly. Dependable cost estimates are often required by customers long before detailed analysis and design activities would produce this information during a ...
Callender, G., Jamieson, D., Vinsen, K.
core
Prediction accuracy measurements as a fitness function for software effort estimation. [PDF]
Springerplus, 2015 Urbanek T +3 more
europepmc +1 more source
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source