Results 61 to 70 of about 150,276 (218)
Improvement of effort estimation accuracy in software projects using a feature selection approach [PDF]
Journal of Advances in Computer Engineering and Technology, 2016 In recent years, utilization of feature selection techniques has become an essential requirement for processing and model construction in different scientific areas.
Zahra Shahpar +3 more
doaj
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
IEEE AccessThe success of software projects is closely linked to accurate effort estimation, driving continuous efforts by researchers to refine estimation methods.
Taghi Javdani Gandomani +3 more
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Applying COCOMO II for a DO-178C Safety-Critical Software Effort Estimation
Journal of Aerospace Technology and Management, 2019 This paper provides a real example of applying COCOMO II as an estimation technique for the required software development effort in a safety-critical software application project following the DO-178C processes. The main goal and contribution of the case
Lucas Pereira dos Santos +1 more
doaj +3 more sources
Toward LLM-aware software effort estimation: a conceptual framework
Frontiers in Artificial IntelligenceSoftware effort estimation has traditionally been grounded in the assumption that development cost is primarily driven by human labor, approximated through proxies such as code size, functional complexity, or perceived task difficulty.
Feisal Alaswad +2 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Evaluation of the accuracy of established patient inspiratory effort estimation methods during mechanical support ventilation. [PDF]
Heliyon, 2023 van Diepen A +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source