Results 61 to 70 of about 173,318 (310)

Can Large-Language Models Replace Humans in Agile Effort Estimation? Lessons from a Controlled Experiment

open access: yesApplied Sciences
Effort estimation is critical in software engineering to assess the resources needed for development tasks and to enable realistic commitments in agile iterations.
Luka Pavlič   +2 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

A systematic review of software development cost estimation studies

open access: yes, 2007
This paper aims to provide a basis for the improvement of software estimation research through a systematic review of previous work. The review identifies 304 software cost estimation papers in 76 journals and classifies the papers according to research ...
Shepperd, MJ, Jørgensen, M
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Effort Estimation in Agile Global Software Development Context

open access: yes, 2014
Both Agile Software Development (ASD) and Global Software Development (GSD) are 21st century trends in the software industry. Many studies are reported in the literature wherein software companies have applied an agile method or practice GSD.
Muhammad Usman   +8 more
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Integrating Emotional Requirements in Use-Case Point Model for Effort Estimation of Healthcare System

open access: yesIEEE Access
The software industry was greatly affected by the pandemic. The emotions and human behavior of software developers and users greatly affected the development of software systems.
Shoaib Hassan   +4 more
doaj   +1 more source

SEffEst: Effort estimation in software projects using fuzzy logic and neural networks [PDF]

open access: yesInternational Journal of Computational Intelligence Systems, 2012
Academia and practitioners confirm that software project effort prediction is crucial for an accurate software project management. However, software development effort estimation is uncertain by nature.
Israel González-Carrasco   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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