Results 1 to 10 of about 401,950 (315)

Evaluation of effect of epidermal growth factor receptor and vascular endothelial growth factor overexpression in survival of patients with glioblastoma multiforme [PDF]

Romanian Journal of Neurology, 2021
Background. In the central nervous system, glioblastoma multiforme (GBM) is one of the most important neoplasms in adults. Amplification of EGFR and VEGF genes is common in GBM. However, the role of overexpression of EGFR and VEGF in survival of patients
Babak Alijani, Hamid Saeidi Saedi, Hadi Hajizadeh Fallah, Ehsan Kazemnejad Leili, Adel Kiumarsi, Sasan Andalib   +5 more
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Immunohistochemical Evaluation of EGFR Expression in Oral Dysplastic and Non-Dysplastic Leukoplakia [PDF]

Journal of Mashhad Dental School, 2023
Background: This study aimed to evaluate the expression of epidermal growth factor receptor (EGFR) in oral leukoplakia with and without dysplasia and normal mucosa by immunohistochemistry.Materials and Methods: In this study, 45 samples of oral ...
Nasrollah Saghravanian, Narges Ghazi, Abdollah Javan rashid, Mohammad Ebrahimi   +3 more
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EGFR Mutations Are Not All the Same: the Importance of Biomarker Testing in Non-small Cell Lung Cancer (NSCLC)—A Podcast Discussion Between Patients and Oncologists

Oncology and Therapy, 2023
This podcast, for healthcare professionals (HCPs), patients, and patient advocates, is a discussion among a panel of two patients (and co-founders of the patient advocacy group EGFR Resisters, https://egfrcancer.org/ ) and two oncologists.
Stephen V. Liu, Ivy B. Elkins, Jill Feldman, Sarah B. Goldberg   +3 more
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The Association between Glycated Hemoglobin and Estimated Glomerular Filtration Rate in Patients with Type 2 Diabetes based on the Hemoglobin Status [PDF]

Journal of Kerman University of Medical Sciences, 2021
Background:The aim of the present study was to examine the association between hemoglobin A1C (HbA1C( and eGFR in patients with type 2 diabetes (T2D). Methods:This cross-sectional study was conducted on 802 patients with T2D visiting Abu Reyhan Clinic of
Hamid Reza Samimagham, Mohammad Tamaddondar, Mitra Kazemi jahromi   +2 more
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Biomarkers to target and silence stemness of breast cancer stem cell model: silencing MDR1 by siRNA

Türk Biyokimya Dergisi, 2022
Aim of the study was to reveal new biomarker genes to target breast cancer stem-like cells (BCSC-like) and then sensitize BCSC-like cells to chemotherapy by silencing MDR1 gene found to be the most suitable target.
Yıldırım Gamze, Kars Meltem D., Kars Gökhan, Kılıç Hamdi Ş.   +3 more
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Glycochenodeoxycholate Promotes Liver Fibrosis in Mice with Hepatocellular Cholestasis

Cells, 2020
Hydrophobic bile salts are considered to promote liver fibrosis in cholestasis. However, evidence for this widely accepted hypothesis remains scarce. In established animal models of cholestasis, e.g., by Mdr2 knockout, cholestasis and fibrosis are both ...
Simon Hohenester, Veronika Kanitz, Andreas E. Kremer, Coen C. Paulusma, Ralf Wimmer, Helen Kuehn, Gerald Denk, David Horst, Ronald Oude Elferink, Ulrich Beuers   +9 more
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Different levels of epidermal growth factor signaling modifies the differentiation of specific cell types in mouse postnatal retina [PDF]

Archives of Biological Sciences, 2019
Epidermal growth factor (EGF) signaling has been implicated in the regulation of the differentiation and proliferation of retinal progenitors. We assessed how different levels of EGF signaling, achieved either by increasing receptor expression or via ...
Ivković Sanja, Jovanović-Macura Irena, Antonijević Tijana, Kanazir Selma, Henrique Domingos   +4 more
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Divergence between serum creatine and cystatin C in estimating glomerular filtration rate of critically ill COVID-19 patients

Renal Failure, 2021
Background The clinical use of serum creatine (sCr) and cystatin C (CysC) in kidney function evaluation of critically ill patients has been in continuous discussion.
Yanan Liu, Peng Xia, Wei Cao, Zhengyin Liu, Jie Ma, Ke Zheng, Limeng Chen, Xuewang Li, Yan Qin, Xuemei Li   +9 more
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Intratumor heterogeneity of driver mutations and TMB distribution in 30 early-stage LUAD patients with multiple lesions

Frontiers in Oncology, 2022
BackgroundDifferentiating multiple pulmonary lesions as multiple primary lung cancer (MLC) or intra-pulmonary metastasis (IPM) is critical. Lung cancer also has a high genetic heterogeneity, which influenced the treatment strategy.
Yuan Qiu, Yuan Qiu, Liping Liu, Liping Liu, Haihong Yang, Haihong Yang, Hanzhang Chen, Hanzhang Chen, Qiuhua Deng, Qiuhua Deng, Dakai Xiao, Dakai Xiao, Yongping Lin, Yongping Lin, Changbin Zhu, Weiwei Li, Di Shao, Wenxi Jiang, Kui Wu, Jianxing He, Jianxing He   +20 more
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UniCAR T cell immunotherapy enables efficient elimination of radioresistant cancer cells

OncoImmunology, 2020
Induction or selection of radioresistant cancer (stem) cells following standard radiotherapy is presumably one of the major causes for recurrence of metastatic disease.
Claudia Arndt, Liliana R. Loureiro, Anja Feldmann, Justyna Jureczek, Ralf Bergmann, Domokos Máthé, Nikolett Hegedüs, Nicole Berndt, Stefanie Koristka, Nicola Mitwasi, Frederick Fasslrinner, Chris Lamprecht, Alexandra Kegler, Anja Hoffmann, Tabea Bartsch, Ayşe Sedef Köseer, Gary Egan, Marc Schmitz, Vaclav Hořejší, Mechthild Krause, Anna Dubrovska, Michael Bachmann   +21 more
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