Results 41 to 50 of about 132,691 (210)

Transforming Growth Factor Alpha Stimulation of Mucosal Tissue Cultures from Head and Neck Squamous Cell Carcinoma Patients Increases Chemoresistance to Cisplatin [PDF]

, 2010
The monoclonal epidermal growth factor receptor ( EGFR) antibody cetuximab (Erbitux(TM)) was recently approved by the European Medicines Agency for the treatment of recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC) in combination ...
Baumeister, Philipp, Ulrich Harréus, Schwenk-Zieger, Sabina, Maximilian Reiter, Philipp Baumeister, Reiter, Maximilian, Sabina Schwenk-Zieger, Harreus, Ulrich   +7 more
core   +1 more source

Perspectives on Drug Product Design Among Patients with Lung Cancer in the United Kingdom

Pulmonary Therapy
Introduction The use of oral anticancer medications has become more prevalent in cancer therapy. This is particularly the case in the management of advanced non-small cell lung cancer (NSCLC).
Joshua R. Coulter, Louis Edward Baig, Amy Antipas, Debra Montague, Angela Terry, Sally-Anne Dews, Michaela Ogden-Barker, Colm Doody, Brett Hauber   +8 more
doaj   +1 more source

A preliminary results of integrated chemotherapy with EGFR receptor tyrosine kinase inhibitors in patients with non-small-cell-lung cancer harboring EGFR mutation

Медицинский совет, 2019
In the open prospective non-randomized single-center study we recruited patients with advanced NSCLC harboring EGFR mutations. Initially there were two months of treatment by gefitinib 250 mg daily.
K. K. Laktionov, D. I. Yudin, V. V. Breder, E. V. Reutova, K. P. Laktionov, D. T. Marinov, D. A. Peregudov, M. S. Ardzinba   +7 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Direct comparison of 3 PCR methods in detecting EGFR mutations in patients with advanced non-small-cell lung cancer [PDF]

, 2012
Epidermal growth factor receptor (EGFR) mutations are predictive of response to EGFR tyrosine kinase inhibitors (TKIs) in NSCLC. Several methods have been used to detect EGFR mutations; however, it is not clear which is the most suitable for use in the ...
Tomonaga, Nanae, Nagayasu, Takeshi, Doi, Seiji, Kohno, Shigeru, Nakamura, Yoichi, Iida, Tetsuya, Yamaguchi, Hiroyuki, Motoshima, Kohei, Mizoguchi, Kosuke, Tsukamoto, Kazuhiro, Nakatomi, Katsumi, Ikeda, Takaya   +11 more
core   +1 more source

Transient changes in serum renalase concentration during long-distance running: The case of an amateur runner under continuous training

Journal of Physical Fitness and Sports Medicine, 2017
Renalase is a recently discovered flavin adenine dinucleotide (FAD)-dependent soluble monoamine oxidase. It is expressed principally in the kidney, but its expression in the heart, brain, and skeletal muscle has also been confirmed.
Yasuko Yoshida, Takehito Sugasawa, Masaya Hoshino, Katsuyuki Tokinoya, Keisuke Ishikura, Hajime Ohmori, Kazuhiro Takekoshi   +6 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Effect of Angiotensin Receptor Blocker and Angiotensin Converting Enzyme Inhibitor on Kidney Function and Blood Potassium Level in Indonesian Type 2 Diabetes Mellitus with Hypertension: A Three-Month Cohort Study

Diabetes, Metabolic Syndrome and Obesity, 2021
Febriana M Puspita,1 Em Yunir,2 Putri S Agustina,1 Rani Sauriasari1 1Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia; 2Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, IndonesiaCorrespondence: Rani ...
Puspita FM, Yunir E, Agustina PS, Sauriasari R   +3 more
doaj  

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Association of an Egfr Intron 1 Snp with Never-Smoking Female Lung Adenocarcinoma Patients

, 2011
Epidermal growth factor receptor (EGFR) plays an important role in the development and progression of a variety of malignant tumors. To test single nucleotide polymorphisms ( SNPs) and haplotypes of the EGFR in modulating the lung cancer susceptibility ...
JOU, YUH-SHAN;HSIAO, CHIN-FU;CHANG, GEE-CHEN;TSAI, YING-HUANG;SU, WU-CHOU;CHEN, YUH-MIN;HUANG, MING-SHYAN;CHEN, HUI-LING;CHEN, CHIEN- JEN;YANG, PAN-CHYR;HSIUNG, CHAO A., 周玉山;蕭金福;張基晟;蔡熒煌;蘇五洲;陳育民;黃明賢;陳惠玲;陳建仁;楊泮池;熊昭   +1 more
core   +1 more source