Results 181 to 190 of about 401,950 (315)

NK cell-mediated tumor cell killing by bispecific innate cell engagers induces ADCC-mediated activation of primary human dendritic cells. [PDF]

Oncoimmunology
Heger L, Kaszubowski T, Amon L, Lehmann CHK, Wingert S, Medina-Echeverz J, Koch J, Hackstein H, Purbojo A, Hartmann A, Alexiou C, Cesnjevar R, Pahl J, Dudziak D.   +13 more
europepmc   +1 more source

Impact of EGFR Genetic Variants on Glioma Risk and Patient Outcome [PDF]

, 2011
Bruno M. Costa, Marta Viana‐Pereira, Ricardo Ferreira Fernandes, Sandra Costa, Paulo Linhares, Ruí Vaz, Céline Pinheiro, Jorge Lima, Paula Soares, Ana Silva, Fernando Pardal, Julia A de Amorim, Rui Nabiço, Rui Almeida, Carlos Alegria, Manuel Melo Pires, Célia Pinheiro, Ernesto Carvalho, Pedro Oliveira, José Manuel Lopes, Rui Manuel Reis   +20 more
openalex   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

Prevalence of <i>EGFR</i> mutations in patients with resected stage I-III non-small cell lung cancer: results from EARLY-EGFR Latin America study. [PDF]

J Thorac Dis
Kajatt EA, Perroud HA, Garcia-Herreros L, Suárez F, Puello Guerrero A, Tejado Gallegos LF, Donner N, Huggenberger R, Corrales L.   +8 more
europepmc   +1 more source

RADA16 and SAAP148 Peptide‐Modified Collagen Self‐Assembled Hydrogels for Accelerated Healing of Infected Wounds

Advanced Science, EarlyView.
Collagen type I (Col I) is integrated with self‐assembling peptide RADA16 and loaded with anti‐bacterial peptide SAAP148 to develop a self‐assembled nano‐microstructure hydrogel (Col I‐RADA16‐SAAP148, CRS) without chemical cross‐linkers. CRS exhibits excellent mechanical properties, sustained SAAP148 release to inhibit bacterial infection, macrophage ...
Qian Liu, Jiawei Wu, Ho‐Pan Bei, Yufei Chen, Yifan Zhang, Xueliang Peng, Fulin Chen, Xin Zhao, Zhuoyue Chen   +8 more
wiley   +1 more source

Uromodulin alleviates fibrosis in acute kidney injury to chronic kidney disease transition by reducing EGFR. [PDF]

Cell Commun Signal
Xing Z, Gong K, Wang N, Bai L, Hu N, Song D, Chen Y.   +6 more
europepmc   +1 more source

The effect of one year lifestyle intervention on eGFR in children and adolescents with overweight, obesity and morbid obesity [PDF]

, 2019
Mark van Dam, Jesse Rijks, Elke Dorenbos, Flore Horuz, Karin van Dael, Anita Vreugdenhil   +5 more
openalex   +1 more source

Reprogramming M2b Macrophages via GPX1 Activation by Selenium Nanoparticles Attenuates Lupus Nephritis

Advanced Science, EarlyView.
SeZM NPs selectively target M2b macrophages through mannose–MRC1 (CD206) recognition, enhance GPX1 biosynthesis, and suppress mitochondrial ROS generation, oxidative stress, and JAK–STAT signaling. This dual regulation reduces pro‐inflammatory cytokine release, limits immune cell infiltration and fibrosis, and preserves renal function, providing a ...
Haoran Lv, Guanning Huang, Hongyu Li, Hanzhi Liang, Huajing Peng, Kefei Wu, Wenfang Chen, Dandan Zhang, Kexin Ma, Yufei Du, Siweier Luo, Yi Zhou, Haiping Mao, Wei Chen, Tianfeng Chen, Yiming Zhou, Qinghua Liu   +16 more
wiley   +1 more source

The Association Between Estimated Glomerular Filtration Rate and All-Cause Mortality in Patients with Dysglycemia in Northeastern Thailand. [PDF]

Diabetes Metab Syndr Obes
Sribenjalak D, Charoensri S, Kritmetapak K, Pongchaiyakul C.   +3 more
europepmc   +1 more source