Results 21 to 30 of about 478,784 (306)

Water-soluble pristine C60 fullerene attenuates acetaminophen-induced liver injury [PDF]

BioImpacts, 2019
Introduction: Oxidative stress has been suggested as the main trigger and pathological mechanism of toxic liver injury. Effects of powerful free radical scavenger С60 fullerene on rat liver injury and liver cells (HepG2 line) were aimed to be discovered.
Halyna Kuznietsova, Oksana Lynchak, Natalia Dziubenko, Tetyana Herheliuk, Yuriy Prylutskyy, Volodymyr Rybalchenko, Uwe Ritter   +6 more
doaj   +1 more source

EGFR‐AS1 Promotes Bladder Cancer Progression by Upregulating EGFR [PDF]

BioMed Research International, 2020
Long noncoding RNAs play an essential role in bladder cancer progression. The role of long noncoding RNA EGFR‐AS1 in bladder cancer needs further study. We used clinical specimens to analyze the relationship between EGFR‐AS1 and bladder cancer patients’ characteristics.
Anbang Wang, Aimin Jiang, Xinxin Gan, Zheng Wang, Jinming Huang, Kai Dong, Bing Liu, Linhui Wang, Ming Chen   +8 more
openaire   +2 more sources

Analysis of Epithelial Growth Factor-Receptor (EGFR) Phosphorylation in Uterine Smooth Muscle Tumors [PDF]

, 2013
Uterine fibroids are the commonest uterine benign tumors. A potential mechanism of malignant transformation from leiomyomas to leiomyosarcomas has beendescribed.
Darius Dian, Antonis Makrigiannakis, Jeschke, Udo, Klaus Friese, Weissenbacher, Tobias, Mayr, Doris, David Roeder, Udo Jeschke, Nina Ditsch, Thomas Vrekoussis, Tobias Weissenbacher, Vrekoussis, Thomas, Dian, Darius, Ditsch, Nina, Friese, Klaus, Doris Mayr, Makrigiannakis, Antonis, Roeder, David   +17 more
core   +1 more source

eGFR [PDF]

Clinical Journal of the American Society of Nephrology, 2009
GFR is the accepted metric for evaluating renal function but measuring it directly (mGFR) can be cumbersome, time-consuming, and costly. The constant infusion method using inulin as the filtration marker, introduced in 1934 by Richards and Smith (1), has undergone many revisions that have now made mGFR easier to perform, although not widely available ...
Richard J. Glassock, Christopher G. Winearls   +1 more
openaire   +1 more source

Computational modelling of cancerous mutations in the EGFR/ERK signalling pathway [PDF]

, 2009
This article has been made available through the Brunel Open Access Publishing Fund - Copyright @ 2009 Orton et al.BACKGROUND: The Epidermal Growth Factor Receptor (EGFR) activated Extracellular-signal Regulated Kinase (ERK) pathway is a critical cell ...
Gormand, A, Adriaens, M.E., Adriaens, Michiel E., Kolch, W, Amelie Gormand, Adriaens, ME, Gormand, A., Sturm, OE, David R Gilbert, Richard J Orton, Walter Kolch, Orton, RJ, Orton, Richard J., Oliver E Sturm, Gilbert, D, Gilbert, David R., Michiel Adriaens, M.E., Michiel E Adriaens, Orton, R.J., Kolch, Walter, Kolch, W., Gilbert, D.R., Sturm, O.E., Sturm, Oliver E., et al., Gormand, Amelie, Gormand, Amelie,, Lund University.   +27 more
core   +1 more source

EGFR [PDF]

Clinical Journal of the American Society of Nephrology, 2008
Reporting estimated glomerular filtration rate (eGFR) with serum creatinine simply provides the information for which the serum creatinine was ordered in the first place. Mass or universal screening is not the purpose of eGFR reporting. Furthermore, such mass screening does not seem justified.
Michal L, Melamed, Carolyn, Bauer, Thomas H, Hostetter   +2 more
openaire   +3 more sources

Improved Biological Impacts of Anti-EGFR Monoclonal Antibody in KRAS-Mutant Colorectal Cancer Cells by Silica-Coated Magnetic Nanoparticle Conjugation [PDF]

Pharmaceutical Sciences
Background: The therapeutic potential of epidermal growth factor receptor (EGFR) targeting in colorectal cancer (CRC) is hindered by the presence of KRAS codon 12 activating mutations, prevalent in approximately 25% of advanced CRC cases.
Maedeh Yousefi, Hamed Farzi-Khajeh, Mostafa Akbarzadeh-Khiavi, Azam Safary, Khosro Adibkia   +4 more
doaj   +1 more source

Modest effect of p53, EGFR and HER-2/neu on prognosis in epithelial ovarian cancer: a meta-analysis [PDF]

, 2009
Background: P53, egfr and her-2/neu are the most frequently studied molecular biological parameters in epithelial ovarian cancer, but their prognostic impact is still unequivocal.
de Jong, S., de Vries, E.G.E., de Bock, G.H.; id_orcid, Boezen, M., Post, W.J., van der Zee, A.G.J., de Vries, E.G.E.; id_orcid, Crijns, A.P.G., de Jong, S.; id_orcid, de Graeff, P., de Bock, G.H.   +10 more
core   +2 more sources

Blockade of Radiation-induced EGFR Nuclear Transport Enhances Radiosensitivity of Human Cervical Cancer

Zhongliu Fangzhi Yanjiu, 2020
Objective To investigate whether the inhibition of EGFR nuclear transport could reduce the radioresistance of human cervical cancer cells. Methods Human cervical cancer CaSki and HeLa cells were exposed to radiation treated with or without Thr654 ...
LI Lu, HUANG Jianming, FENG Mei, QI Yunxiang, MA Shiqi, TAN Mingyu, LANG Jinyi   +6 more
doaj   +1 more source

Canine parvovirus induces G1/S cell cycle arrest that involves EGFR Tyr1086 phosphorylation

Virulence, 2020
Canine parvovirus (CPV) has been used in cancer control as a drug delivery vehicle or anti-tumor reagent due to its multiple natural advantages. However, potential host cell cycle arrest induced by virus infection may impose a big challenge to CPV ...
Xiaofeng Dai, Xuanhao Zhang, Yujie Miao, Peiyu Han, Jianying Zhang   +4 more
doaj   +1 more source