Results 221 to 230 of about 368,987 (265)
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ACS Chemical Neuroscience, 2021
Recent findings showed that preformed fibrils (PFFs) of misfolded proteins, including α-synuclein (α-syn) and amyloid-β (Aβ), activate EGFR in cell cultures and animal models of amyloid propagation. Comparing these supramolecular structures to normal EGFR ligands such as EGF and HB-EGF suggests that these PFFs might trigger the formation of high order ...
Omid Tavassoly, Iman Tavassoly
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Recent findings showed that preformed fibrils (PFFs) of misfolded proteins, including α-synuclein (α-syn) and amyloid-β (Aβ), activate EGFR in cell cultures and animal models of amyloid propagation. Comparing these supramolecular structures to normal EGFR ligands such as EGF and HB-EGF suggests that these PFFs might trigger the formation of high order ...
Omid Tavassoly, Iman Tavassoly
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Nature Reviews Cancer, 2021
Gao, Xia, Li, Zhang et al. show that a circular RNA-encoded variant of E-Cadherin stimulates EGFR signalling independently of EGF, and contributes to glioblastoma tumorigenesis and anti-EGFR therapy resistance.
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Gao, Xia, Li, Zhang et al. show that a circular RNA-encoded variant of E-Cadherin stimulates EGFR signalling independently of EGF, and contributes to glioblastoma tumorigenesis and anti-EGFR therapy resistance.
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Clonal dominance of EGFR and efficacy of EGFR-tyrosine kinase inhibitors (EGFR-TKIs) in NSCLC.
Journal of Clinical Oncology, 2020e21501 Background: Though EGFR mutations in lung cancer are identified most often on the trunks of tumor phylogenetic trees in early stage, whether EGFR would always be the dominant clone in the advanced stage is unknown, as cancer evolution often follows a branched trajectory, with divergent subclones evolving simultaneously.
Xinghao Ai +14 more
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European Journal of Cancer, 2001
Elevated levels of the epidermal growth factor receptor (EGFR), a growth-factor-receptor tyrosine kinase, and/or its cognate ligands have been identified as a common component of multiple cancer types and appear to promote solid tumour growth. This article examines the relationship between EGFR expression and cancer prognosis based on literature ...
R I, Nicholson, J M, Gee, M E, Harper
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Elevated levels of the epidermal growth factor receptor (EGFR), a growth-factor-receptor tyrosine kinase, and/or its cognate ligands have been identified as a common component of multiple cancer types and appear to promote solid tumour growth. This article examines the relationship between EGFR expression and cancer prognosis based on literature ...
R I, Nicholson, J M, Gee, M E, Harper
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EGFR mutations and EGFR tyrosine kinase inhibitors
The Lancet Oncology, 2015Valter, Torri +2 more
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CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance
Cancer Cell, 2023Thiruvengadam Arumugam +2 more
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EGFR signaling in renal fibrosis
Kidney International Supplements, 2014Na Liu, Shougang Zhuang
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