Results 21 to 30 of about 401,950 (315)

Structural Diversity and Role of Phytochemicals against P38-α Mitogen-activated Protein Kinase and Epidermal Growth Factor Receptor Kinase Domain: A Privileged Computational Approach

Journal of Pure and Applied Microbiology, 2021
Computational databases and tools in recent times have been proved to provide an essential aid for anticancer studies in the field of oncology. Molecular docking studies facilitate the structural diversity of plant-derived phytomolecules having ...
Amar Shankar, S.M. Gopinath, Shiva Prasad Kollur, P. Sushma, Anisha S. Jain, Sharanagouda S. Patil, Chandrashekar Srinivasa, Shivalingaiah, Chandan Shivamallu   +8 more
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Amplification of cycline D1, c-myc and EGFR oncogenes in tumour samples of breast cancer patients [PDF]

Journal of Medical Biochemistry, 2013
Background: Breast cancer is the most common form of cancer in women. It arises from multiple genetic changes in oncogenes and tumor suppressor genes.
Tanić Nasta, Milinković Vedrana, Dramićanin Tatjana, Nedeljković Milica, Stanković Tijana, Milovanović Zorka, Šušnjar Snežana, Milošević Verica, Šosić-Jurjević Branka, Džodić Radan, Tanić Nikola   +10 more
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The efficacy and safety of first-line therapy for the epidermal growth factor receptor mutant non-small cell lung cancer in older versus younger patients: A pooled analysis of two randomized controlled trials

Cancer Research, Statistics, and Treatment, 2020
Background: There is a scarcity of data to guide the management of older patients with cancer. We therefore conducted this study to compare the outcomes and toxicities in older versus younger patients with an epidermal growth factor receptor (EGFR ...
Akhil Kapoor, Vanita Noronha, Vijay M Patil, Amit Joshi, Nandini Menon, Anuradha Chougule, Pratik Chandrani, Vaishakhi Trivedi, Vichitra Behel, Rajiv Kumar, Abhishek Mahajan, Amit Janu, Kumar Prabhash   +12 more
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Access to Diagnostics and Treatment for People With Metastatic EGFR-Positive NSCLC: Lessons From Project PRIORITY

JTO Clinical and Research Reports
Introduction: The treatment landscape for people diagnosed with EGFR-mutated (EGFR-m) NSCLC has rapidly evolved, yet there remains limited self-reported information about the lived experience.
Jill Feldman, MA, Ivy Elkins, MBA, Zofia Piotrowska, MD, Bellinda L. King-Kallimanis, PhD, Tendai Chihuri, MD, Carly Johnson, BS, Alecia Clary, PhD, Teri Kennedy, MA, Upal Basu Roy, PhD, MPH   +8 more
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10-Year Evaluation of Adherence and Satisfaction with Information about Tolvaptan in ADPKD: A Single-Center Pilot Study

Patient Preference and Adherence, 2021
Holger Schirutschke, Peter Gross, Alexander Paliege, Christian Hugo University Hospital Carl Gustav Carus at the Technische, Universität Dresden, Department of Internal Medicine III, Division of Nephrology, Dresden, GermanyCorrespondence: Holger ...
Schirutschke H, Gross P, Paliege A, Hugo C   +3 more
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Thyroid Function Disorders in Patients with Chronic Kidney Disease

Medical Journal of Babylon, 2022
Background: Various thyroid functional test abnormalities are commonly observed in chronic kidney disease (CKD) due to alterations in thyroid hormone synthesis, metabolism, and regulation.
Hussein Yousif Sinjari, Jassim Muhammed Ibrahim   +1 more
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Preliminary Study on Detection of Circulating Tumor Cells in Lung Cancer by EGFR/Vimentin/Folic Acid Magnetic Sphere

Chinese Journal of Lung Cancer, 2020
Background and Objective Circulating tumor cells (CTC) play an important role in the screening and prognosis of lung cancer, but the low efficiency and specificity of CTC isolation obviously restrict its clinical application. The purpose of this study is
Guolei LI, Yun WANG, Guoliang TAN, Yuan LIU, Zhao XU, Hao FENG, Wei XING, Zhifeng XU   +7 more
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Renal Resistive İndeks’in Hafif Orta Böbrek Yetersizliği Olan Koroner Arter Hastalarında Hastalık Şiddetini Belirlemedeki Yeri

Ankara Medical Journal, 2016
Amaç: Çalışmamızda hafif orta renal yetersizliği olan hastalarda renal resistive indeksini (RRİ)saptayarak bunun renal fonksiyonlar ve koroner arter hastalığının (KAH) şiddetiyle ilişkisini araştırdık.Materyal ve Metot: Çalışmaya koroner angiografisi ...
Bircan Alan, Adem Aktan, Abdurrahim Dusak   +2 more
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Nanobody-targeted photodynamic therapy for the treatment of feline oral carcinoma: a step towards translation to the veterinary clinic

Nanophotonics, 2021
Nanobody-targeted photodynamic therapy (NB-PDT) has been developed as a potent and tumor-selective treatment, using nanobodies (NBs) to deliver a photosensitizer (PS) specifically to cancer cells. Upon local light application, reactive oxygen species are
Beltrán Hernández Irati, Grinwis Guillaume C.M., Di Maggio Alessia, van Bergen en Henegouwen Paul M.P., Hennink Wim E., Teske Erik, Hesselink Jan W., van Nimwegen Sebastiaan A., Mol Jan A., Oliveira Sabrina   +9 more
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Elevated homocysteine and differential risks of the renal function decline in hypertensive patients

Clinical and Experimental Hypertension, 2020
Importance In several studies, homocysteine (hcy) is a documented risk for predicting renal function decline. The differential effects between various levels of hcy have yet to be quantified.
Chunlei Liu, Lin Lin, Rui Xu
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