Killifish eggs can disperse via gut passage through waterfowl [PDF]
Ecology, 2019 Peer ...
Silva, G. G. +9 more
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Predicting Egg Passage Adaptations to Design Better Vaccines for the H3N2 Influenza Virus [PDF]
Viruses, 2022 Seasonal H3N2 influenza evolves rapidly, leading to an extremely poor vaccine efficacy. Substitutions employed during vaccine production using embryonated eggs (i.e., egg passage adaptation) contribute to the poor vaccine efficacy (VE), but the evolutionary mechanism remains elusive. Using an unprecedented number of hemagglutinin sequences (n = 89,853),
Yunsong Liu +7 more
openaire +5 more sources
Passage of Meloidogyne Eggs in Human Stool: Forgotten, but Not Gone [PDF]
Journal of Clinical Microbiology, 2015 Recently, we were involved in a project to train staff from the Atoifi Adventist Hospital (AAH) in East Kwaio, Malaita, Solomon Islands, in applied research and laboratory methods. The project, run by AAH, included the performance of a cross-sectional survey for soil-transmitted helminths in ...
Bradbury, Richard S., Speare, Rick.
openaire +3 more sources
Viral proteins expressed in the protozoan parasite Eimeria tenella are detected by the chicken immune system [PDF]
, 2016 BACKGROUND: Eimeria species are parasitic protozoa that cause coccidiosis, an intestinal disease commonly characterised by malabsorption, diarrhoea and haemorrhage that is particularly important in chickens.
Blake, D P +6 more
core +3 more sources
BMC Veterinary Research, 2018 Background Vaccines constitute a unique selective pressure, different from natural selection, drives the evolution of influenza virus. In this study, A/Chicken/Shanghai/F/1998 (H9N2) was continually passaged in specific pathogen-free embryonated chicken ...
Haiyun Jin +8 more
doaj +1 more source
Viral factors in influenza pandemic risk assessment [PDF]
, 2016 The threat of an influenza A virus pandemic stems from continual virus spillovers from reservoir species, a tiny fraction of which spark sustained transmission in humans.
Barclay, Wendy +18 more
core +4 more sources
The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication [PDF]
, 2014 Most RNA viruses infecting mammals and other vertebrates show profound suppression of CpG and UpA dinucleotide frequencies. To investigate this functionally, mutants of the picornavirus, echovirus 7 (E7), were constructed with altered CpG and UpA ...
Atkinson, Nicky J. +3 more
core +2 more sources
A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.
PLoS Pathogens, 2017 The effectiveness of the annual influenza vaccine has declined in recent years, especially for the H3N2 component, and is a concern for global public health.
Nicholas C Wu +8 more
doaj +1 more source
Viruses, 2019 The embryonated chicken egg (ECE) is routinely used for the laboratory isolation and adaptation of Bluetongue virus (BTV) in vitro. However, its utility as an alternate animal model has not been fully explored.
Fabian Z. X. Lean +11 more
doaj +1 more source
Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation. [PDF]
, 2005 Maternal embryonic leucine zipper kinase (MELK) was previously identified in a screen for genes enriched in neural progenitors. Here, we demonstrate expression of MELK by progenitors in developing and adult brain and that MELK serves as a marker for self-
Bajpai, Ruchi +17 more
core +2 more sources