Results 151 to 160 of about 282,688 (383)

Gasdermin D‐Mediated Pyroptosis Exerts Two Opposite Effects of Resisting Enzymatic Digestion and Expanding Inflammatory Response in Acute Pancreatitis

open access: yesAdvanced Science, EarlyView.
Gasdermin D (GSDMD) does not only reduce pancreatic enzyme synthesis but also induces pancreatic acinar cells to express mucin 1 (MUC1), which forms a barrier to prevent digestive enzyme‐mediated digestion. However, GSDMD can promote the secretion of inflammatory cytokines by macrophages and aggravate pancreatic histological injury by expanding ...
Chaoxu Liu   +10 more
wiley   +1 more source

Effect of broodstock holding environment on egg quality in farmed brown trout (Salmo trutta) [PDF]

open access: yes, 2016
Brown trout (Salmo trutta) broodstock from a single population were separated prior to spawning and exposed to two different holding environments: a ‘raceway system’ and a ‘tank system’. Eggs were stripped from females and 13 measures of egg quality
Adams, C.E.   +4 more
core   +1 more source

Gut Microbiota Modulates Obesity‐Associated Skeletal Deterioration Through Macrophage Aging and Grancalcin Secretion

open access: yesAdvanced Science, EarlyView.
Obese gut‐microbiota derived lipopolysaccharides (LPS) induce bone marrow macrophage senescence and GCA secretion via activating TLR4/NF‐κB/MAPKs pathway. Clinically, obese patients are associated with higher serum GCA levels. Mice with depletion of GCA gene show resistance to skeletal deterioration caused by obesity and LPS‐induced chronic ...
Min Huang   +16 more
wiley   +1 more source

3D evolution of protein networks and lipid globules in heat-treated egg yolk [PDF]

open access: yesarXiv
Upon heating, egg yolk transforms from a liquid to a gel due to protein denaturation. This process can serve as a useful model to better understand protein denaturation in general. Using x-ray holographic tomography, we investigated the structural changes in egg yolk during boiling without the need for complex sample fixation or drying.
arxiv  

Changes in Serum Protein Profile in Laying Hens Housed in a Cage-Free System

open access: yesVeterinary Medicine International
The objective of this study was to characterize the distribution of serum proteins in laying hens reared under cage-free open farm conditions and to evaluate the changes in the concentrations of serum protein fractions throughout the 1-year laying period.
Csilla Tóthová   +5 more
doaj   +1 more source

Trypstatin as a Novel TMPRSS2 Inhibitor with Broad‐Spectrum Efficacy against Corona and Influenza Viruses

open access: yesAdvanced Science, EarlyView.
Trypstatin, a 61‐amino acid Kunitz‐type protease inhibitor derived from human Bikunin, potently inhibits TMPRSS2 and related proteases. It blocks spike‐ and hemagglutinin‐mediated entry of multiple respiratory viruses in vitro reduces SARS‐CoV‐2 replication in human airway cultures, and lowers viral load and symptoms in infected hamsters, demonstrating
Jan Lawrenz   +24 more
wiley   +1 more source

Simple Protein Foaming‐Derived 3D Segregated MgO Networks in Epoxy Composites with Outstanding Thermal Conductivity Properties

open access: yesAdvanced Science, EarlyView.
MgO‐based composites with highly interconnected filler networks are fabricated using a simple, eco‐friendly protein foaming method. Liquid‐phase‐assisted sintering enhanced bonding with the matrix. The interconnected structured filler composites exhibit significantly improved thermal conductivity, exceeding that of pure epoxy, randomly dispersed ...
Su‐Jin Ha   +6 more
wiley   +1 more source

What is the optimal anthropoid primate diet? [PDF]

open access: yesarXiv, 2001
Following Socrates' advice "You should learn all you can from those who know. Everyone should watch himself throughout his life, and notice what sort of meat and drink and what form of exercise suit his constitution, and he should regulate them in order to enjoy good health." Based on biological, chemical and physical considerations I have attempted to
arxiv  

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