Recent progress in the research of Eosinophilic GastroIntestinal Diseases (EGIDs)
Eosinophilic esophagitis (EoE) and eosinophilic gastroenteritis (EGE), which are included in eosinophilic gastrointestinal disorders (EGIDs), are allergic gastrointestinal diseases mainly caused by food allergens, which features dense infiltration of eosinophiles in the gastrointestinal mucosa.
Norihisa Ishimura +2 more
exaly +4 more sources
Eosinophilic gastrointestinal disorders: variations in eosinophilic counts among investigators and staining methods [PDF]
Objective: Eosinophilic gastrointestinal disorders (EGIDs) are pathologically diagnosed by manually counting the eosinophils in biopsy tissue under microscopy.
Mina Ikeda +18 more
doaj +2 more sources
Knowledge and practice regarding eosinophilic gastrointestinal disorders other than eosinophilic esophagitis among pediatric gastroenterologists of the Latin American Society for Pediatric Gastroenterology, Hepatology, and Nutrition. [PDF]
Abstract Objective Evaluating clinical practices in the management of non‐esophageal eosinophilic gastrointestinal disorders (non‐EoE EGIDs) among pediatric gastroenterologists in Latin America. Methods A cross‐sectional descriptive study was conducted using a survey distributed via the REDCap platform.
Paz S +17 more
europepmc +2 more sources
Biologics for eosinophilic oesophagitis: a systematic review and meta-analysis [PDF]
Objective Advancing the understanding of the pathophysiology of eosinophilic oesophagitis (EoE) and other eosinophilic gastrointestinal diseases (EGIDs) has spurred research into targeted biological therapies, while the conclusive therapeutic efficacy of
Beibei Zeng +7 more
doaj +2 more sources
Behind the scenes: Primary immunodeficiencies in pediatric eosinophilic gastrointestinal diseases. [PDF]
Using a multifaceted approach combining medical history, JMF warning signs, physical examination, and comprehensive immunological evaluation, we identified a considerable frequency of PIDs among pediatric patients with EGID, predominantly antibody deficiencies. JMF warning signs were present in only a minority of patients.
Baskin K +10 more
europepmc +2 more sources
Eosinophilic gastrointestinal disorders: new perspectives and the emerging role of biological therapies [PDF]
The advent of biological drugs has opened up new therapeutic possibilities in the field of eosinophilic gastro-intestinal diseases (EGIDs). EGIDs are chronic inflammatory diseases of the gastrointestinal tract unrelated to drugs or infections, and ...
Francesca Losa, Arianna Cingolani
doaj +1 more source
Recent topics on gastrointestinal allergic disorders [PDF]
Gastrointestinal (GI) allergies are broadly associated with food allergies and divided into groups based on the degree of allergen-specific immunoglobulin E (IgE) involvement: IgE-mediated, non-IgE-mediated, and mixed.
Yoshiyuki Yamada
doaj +1 more source
Esophageal Involvement in Non-Eosinophilic Esophagitis Eosinophilic Gastrointestinal Diseases: Association With Esophageal Symptoms and Gastric Involvement. [PDF]
JGH Open, Volume 10, Issue 7, July 2026.
Abe Y +5 more
europepmc +2 more sources
Update on biologic and small molecules treatments in pediatric allergic diseases. [PDF]
This graphical abstract summarizes key targets, mechanisms of action, and indications of biologic and small molecules treatments in pediatric allergic diseases.abbreviations : BAS, basophil; BTK, Bruton tyrosine kinase; cDC, conventional dendritic cell; IgE, immunoglobulin E; FCER1, high affinity IgE receptor; IL, interleukin; IL4R, IL4 receptor; JAK ...
den Dekker HT +10 more
europepmc +2 more sources
Gastrointestinal manifestations during oral immunotherapy: A guide for pediatric allergists. [PDF]
Gastrointestinal manifestations occurring during oral immunotherapy (OIT) encompass a spectrum of conditions ranging from immediate IgE‐mediated reactions to delayed eosinophil‐associated disorders, including eosinophilic esophagitis. Because symptoms may overlap with other gastrointestinal diseases, a structured assessment based on symptom timing ...
Votto M +11 more
europepmc +2 more sources

