Results 31 to 40 of about 639 (161)

Eosinophilic gastrointestinal diseases: current perspectives on pathogenesis and management [PDF]

open access: yesExploration of Asthma & Allergy
Eosinophilic gastrointestinal diseases (EGIDs) are a group of chronic conditions, characterized by an excessive accumulation of eosinophils in various areas of the mucosal of the gastrointestinal (GI) tract.
Georgia Papaiakovou   +4 more
doaj   +1 more source

Pathophysiology of Non-IgE-Mediated Food Allergy

open access: yesImmunoTargets and Therapy, 2021
Shouling Zhang, Scott Sicherer, M Cecilia Berin, Amanda Agyemang Department of Pediatrics, Division of Allergy and Immunology, Icahn School of Medicine at Mount Sinai, Kravis Children’s Hospital, The Elliot and Roslyn Jaffe Food Allergy Institute, New ...
Zhang S   +3 more
doaj  

Heterogeneity of Intestinal Tissue Eosinophils: Potential Considerations for Next-Generation Eosinophil-Targeting Strategies

open access: yesCells, 2021
Eosinophils are implicated in the pathophysiology of a spectrum of eosinophil-associated diseases, including gastrointestinal eosinophilic diseases (EGIDs).
Joanne C. Masterson   +4 more
doaj   +1 more source

Differential Roles for IL‐4Rα and IL‐13Rα1 in Immune Cell Infiltration and Epithelial Remodeling in Experimental Eosinophilic Gastritis

open access: yesAllergy, EarlyView.
This study described the development of an experimental model for eosinophilic gastritis (EoG). Experimental EoG recapitulates histopathological features of human disease. including foveolar elongation, fibrosis, eosinophilia, mastocytosis and shared transcriptional programs.
Anish Dsilva   +7 more
wiley   +1 more source

Eosinophilic gastrointestinal diseases – Pathogenesis, diagnosis, and treatment

open access: yesAllergology International, 2019
Eosinophilic gastrointestinal diseases (EGIDs) are divided into eosinophilic esophagitis (EoE) and eosinophilic gastroenteritis (EGE), depending on the involved gastrointestinal tract, though both are considered to be chronic Th2-type allergic diseases ...
Yoshikazu Kinoshita   +2 more
doaj   +1 more source

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

open access: yesBritish Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral   +3 more
wiley   +1 more source

Balancing immune responses: regulatory cells in eosinophilic gastrointestinal disorders

open access: yesFrontiers in Immunology
Eosinophilic gastrointestinal disorders (EGIDs) are a group of conditions characterized by an abnormal accumulation of eosinophils in the gastrointestinal tract, leading to inflammation and tissue damage.
Nassim Kheshtchin   +6 more
doaj   +1 more source

The Dynamics of Language Shift among Lawa-Speaking Families in Northern Thailand

open access: yesJournal of the Southeast Asian Linguistics Society, 2022
This paper examines Lawa language shift, vitality, and endangerment on the family level in Northern Thailand using a six-question set adapted from the five key questions of the Expanded Graded Intergenerational Disruption Scale (EGIDS).
Panyawuthakrai, Rakkhun   +1 more
doaj  

Allergy and eosinophil-associated gastrointestinal disorders (EGID) [PDF]

open access: yesCurrent Opinion in Immunology, 2008
Eosinophil-associated gastrointestinal disorders (EGIDs) are characterized by an inappropriate accumulation of eosinophils within the gastrointestinal tract. The underlying etiology and pathophysiology that lead to the development of EGID are far from elucidated. However, there is growing evidence to support the role of aeroallergens and food allergens
Charles W, DeBrosse, Marc E, Rothenberg
openaire   +2 more sources

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

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