Results 51 to 60 of about 7,056 (256)

Breaking Down Walls and Building Bridges: A Study of Cross-Racial Interactions across Two Predominantly White Campuses

open access: yesJournal Committed to Social Change on Race and Ethnicity, 2017
We examined predictors of self-reported cross-racial interactions (CRIs) by exploring ego networks for 355 Black and White undergraduates at two predominantly White institutions (PWIs).
Tabitha Grier-Reed   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Evolution Analysis of Call Ego-Networks [PDF]

open access: yes, 2016
With the realization of networks in many of the real world domains, research work in network science has gained much attention now-a-days. The real world interaction networks are exploited to gain insights into real world connections. One of the notion is to analyze how these networks grow and evolve.
Shazia Tabassum, João Gama 0001
openaire   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

HIV disclosure in the social networks of adolescents with HIV in Cape Town, South Africa

open access: yesFrontiers in Reproductive Health
BackgroundLittle is known about HIV status disclosure within the social networks of adolescents with perinatally-acquired HIV (APHIV) in sub-Saharan Africa, where HIV prevalence is high and stigma surrounding HIV is pervasive.
Marta I. Mulawa   +14 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Personal Network Composition and Cognitive Reflection Predict Susceptibility to Different Types of Misinformation

open access: yesConnections
Despite a rapid increase in research on the underpinnings of misinformation susceptibility, scholars still disagree about the relative impacts of social context and individual cognitive factors.
Facciani Matthew   +1 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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