Results 101 to 110 of about 8,038 (216)

No differences in nasal tissue inflammatory cells and adhesion molecules (iCAM-1 and vCAM-1) comparing EGPA with eosinophilic chronic sinusitis with polyposis.

, 2019
Background An example of aggressive eosinophilic polyposis can be found in eosinophilic granulomatosis with polyangiitis (EGPA). Intercellular adhesion molecule-1 (iCAM-1) and vascular cell adhesion molecule-1 (vCAM-1) play a part in mediating the ...
Felicetti M, Schiavon F, Parrino D, Brescia G, Marioni G., Cappellesso R, Fassina A, Padoan R, Martini A, Zanoletti E, Zanotti C, Cangiano D, Giacomelli L, Cinetto F, Nicolè L   +14 more
core   +1 more source

Case Report: Coadministration of TNF-α blockade as an effective adjunctive strategy in the treatment of ANCA-negative EGPA with refractory peripheral neuropathy

Frontiers in Pharmacology
Eosinophilic granulomatosis with polyangiitis (EGPA) is characterized by abnormal eosinophilia and extravascular eosinophilic granuloma formation. Conventional treatments combining glucocorticoids and immunosuppressants can alleviate the condition in ...
Dabin Tang, Dabin Tang, Yubao Jiang, Yubao Jiang, Shuo Yang, Shuo Yang, Jiaxin Wei, Jiaxin Wei, Jingjing Xie, Jingjing Xie, Jianyong Zhang, Jianyong Zhang   +11 more
doaj   +1 more source

Serum biomarkers of patients with EGPA in remission and at relapse.

, 2015
Data are shown as median (range in parenthesis); EGPA: eosinophilic granulomatosis with polyangiitis (Churg-Strauss); LR, Logistic regression analysis as described in Materials and Methods; MWU, Mann Whitney U test; n, number of visitsSerum biomarkers of
David Cuthbertson (188652), Peter A. Merkel (188721), Simon Carette (188665), Bastian Oppl (713196), Christian Dejaco (12618), Nader Khalidi (713199), Gary Hoffman (713198), Paul Monach (713197), Jochen Zwerina (11574), Carol Langford (713201), Steven Ytterberg (713203), Curry Koening (713200), Philip Seo (188695), Ulrich Specks (972), Kathleen McKinnon-Maksimowicz (713202)   +14 more
core   +1 more source

PO:35:220 | IgG anti-pentraxin 3 autoantibodies distinguish eosinophilic granulomatosis with polyangiitis from severe eosinophilic asthma and chronic rhinosinusitis with nasal polyps

Reumatismo
Background. Eosinophilic granulomatosis with polyangiitis (EGPA) typically presents with severe eosinophilic asthma (SEA) and chronic rhinosinusitis with nasal polyps (CRSwNP), often preceding systemic vasculitis by years.
Società Italiana di Reumatologia
doaj  

Mepolizumab has clinical benefits including oral corticosteroid sparing irrespective of baseline EGPA characteristics

ERJ Open Research
Background The Mepolizumab in Relapsing or Refractory EGPA (MIRRA) trial (GSK ID: 115921/NCT02020889) demonstrated that mepolizumab increased remission time and reduced oral corticosteroid (OCS) use compared with placebo in patients with relapsing or ...
David R.W. Jayne, Benjamin Terrier, Bernhard Hellmich, Paneez Khoury, Lee Baylis, Jane H. Bentley, Jonathan Steinfeld, Steven W. Yancey, Namhee Kwon, Michael E. Wechsler, Praveen Akuthota   +10 more
doaj   +1 more source

Comparative Insights on IL-5 Targeting with Mepolizumab and Benralizumab: Enhancing EGPA Treatment Strategies

Eosinophilic granulomatosis with polyangiitis (EGPA) is a necrotizing vasculitis characterized by extravascular granulomas and eosinophilia in both blood and tissues.
Ryuhei Ishihara, Ryu Watanabe, Mayu Shiomi, Takashi Nakazawa, Motomu Hashimoto, Sayaka Tanaka   +5 more
core   +1 more source

Effectiveness of explicit guidance and practices on abstraction (EGPA): Focusing on computational tasks in a fifth-grade STEM-integrative robotic education program

Educational Technology & Society
Developing students’ computational thinking has emerged as a crucial objective across K-12 curricula nationwide. Particularly, abstraction is the cornerstone of computational thinking, but endeavors of cultivating students’ abstract thinking have not ...
Yingxiao Qian and Ikseon Choi
doaj   +1 more source

Heterogeneity and individualized therapy for eosinophilic granulomatosis with polyangiitis

Therapeutic Advances in Respiratory Disease
Eosinophilic granulomatosis with polyangiitis (EGPA), as a heterogeneous component of antineutrophil cytoplasmic antibody-associated vasculitis, may be induced by a series of environmental and genetic factors, involved with a variety of immune cells and ...
Lijuan Hua, Min Xie
doaj   +1 more source

TCR GAMMA CLONALITY ASSESSED BY NGS DOES NOT HELP TO DISTINGUISH EGPA FROM HES

, 2017
Background: Hypereosinophilia-associated syndromes are a heterogeneous group of diseases characterized by sustained and elevated blood eosinophilia with evidence of eosinophil-induced organ damage.
Mosca, M, Tarrini, G, R. Grossi, G. Tarrini, M. Latorre, Ferro, F, I. Petrini, Elefante, E, S. Grassi, Grassi, S,  M. Mosca, Metelli, MR, Petrini, M, E. Elefante, Petrini, I, F. Ferro, Grossi, R, F. Guerrini, N. Pisanti, Guerrini, F,  MR. Metelli, Latorre, M, Baldini, C,  E. Ciabatti ,  C. Baldini, S. Galimberti, Galimberti, S, PIsanti, N, M. Petrini, Ciabatti, E   +29 more
core  

MYOCARDITIS SECONDARY TO EGPA: THE EOSINOPHILIC RAID [PDF]

Chest, 2019
Ojobumijo Agbaji, Aparna Das, Anupam Kumar   +2 more
openaire   +1 more source