Results 31 to 40 of about 29,775 (173)

Numerical Investigation on Effects of Assigned EGR Stratification on a Heavy Duty Diesel Engine with Two-Stage Fuel Injection

Energies, 2018
External exhaust gas recirculation (EGR) stratification in diesel engines contributes to reduction of toxic emissions. Weak EGR stratification lies in that strong turbulence and mixing between EGR and intake air by current introduction strategies of EGR.
Zhaojie Shen, Wenzheng Cui, Xiaodong Ju, Zhongchang Liu, Shaohua Wu, Jianguo Yang   +5 more
doaj   +1 more source

Early Growth Response 1 Suppresses Macrophage Phagocytosis by Inhibiting NRF2 Activation Through Upregulation of Autophagy During Pseudomonas aeruginosa Infection

Frontiers in Cellular and Infection Microbiology, 2022
Pseudomonas aeruginosa is an opportunistic pathogen that causes life-threatening infections in cystic fibrosis patients and immunocompromised individuals.
Zheng Pang, Yan Xu, Qingjun Zhu, Qingjun Zhu   +3 more
doaj   +1 more source

Epigallocatechin-3-gallate inhibits transforming-growth-factor-β1-induced collagen synthesis by suppressing early growth response-1 in human buccal mucosal fibroblasts

Journal of the Formosan Medical Association, 2017
Transforming growth factor (TGF)-β is a key regulator in the pathogenesis of oral submucous fibrosis (OSF). Early growth response (Egr)-1 is essential for fibrotic responses to TGF-β.
Yu-Ping Hsieh, Hsin-Ming Chen, Hung-Ying Lin, Hsiang Yang, Jenny Zwei-Chieng Chang   +4 more
doaj   +1 more source

Epigenetic induction of EGR-1 expression by the amyloid precursor protein during exposure to novelty. [PDF]

PLoS ONE, 2013
Following transcriptome comparison of primary cultures isolated from brain of mice expressing or not the amyloid precursor protein APP, we found transcription of the EGR-1 gene to be regulated by APP.
Aurélie Hendrickx, Nathalie Pierrot, Bernadette Tasiaux, Olivier Schakman, Jean-Pierre Brion, Pascal Kienlen-Campard, Charles De Smet, Jean-Noël Octave   +7 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer

Advanced Science, EarlyView.
Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian, Teizo Yoshimura, Kun Zhao, Chunning Li, Tong Gao, Ziyi Wang, Masayoshi Fujisawa, Toshiaki Ohara, Akihiro Matsukawa   +8 more
wiley   +1 more source

Effects of rail pressure control on fuel consumption, emissions and combustion parameters in a turbocharged diesel engine

Cogent Engineering, 2020
The influence of rail pressure control on fuel consumption, emissions and combustion in an automotive downsized turbocharged diesel engine was investigated, considering different operating modes in three-part load working conditions.
Giorgio Zamboni, Massimo Capobianco
doaj   +1 more source

Fluorescent Hydrogel‐Based Strain Sensor With Machine Learning‐Augmented Performance

Advanced Intelligent Discovery, EarlyView.
Fluorescent hydrogel strain sensor based on carbon quantum dots enabling optical readout of deformation through strain‐dependent emission changes, coupled with Random Forest analysis to capture nonlinear fluorescence‐concentration relationships and identify optimal sensing conditions. Hydrogels are ideal matrices for bio‐integrated wearable sensors due
Tailai Chen, Tianlong Liu, Chao Lu, Rimsha Malik, Jin Zhang   +4 more
wiley   +1 more source

EGR-1 3’UTR is targeted by HCMV miR-US22.

, 2019
(A) One miR-US22 target site is present in the EGR-1 3’UTR. The seed sequence is indicated; the arrows label the bases that were mutated to disrupt miR-US22 binding to the target site.
Lindsey B. Crawford (7865579), Jay A. Nelson (7865576), Jason Buehler (2803843), Jennifer Mitchell (243882), Meaghan H. Hancock (3338148), Felicia Goodrum (190077), Iliyana Mikell (120166)   +6 more
core   +1 more source

Ranking of four dual loop EGR modes [PDF]

, 2023
Modern Diesel engines contain sophisticated control systems to keep their environmental impact low for sustainable road transport. One of these systems is the dual loop exhaust gas recirculation, which can change combustion properties in several ways ...
Nyerges, László Ádám, Zöldy, Máté
core   +1 more source