Results 41 to 50 of about 29,775 (173)

Sustained Egr-1 Response via p38 MAP Kinase Signaling Modulates Early Immune Responses of Dendritic Cells Parasitized by Toxoplasma gondii

Frontiers in Cellular and Infection Microbiology, 2019
As a response to a diverse array of external stimuli, early growth response protein 1 (Egr-1) plays important roles in the transcriptional regulation of inflammation and the cellular immune response.
Arne L. ten Hoeve, Mohamed-Ali Hakimi, Antonio Barragan   +2 more
doaj   +1 more source

Hyperglycemia: GDNF-EGR1 pathway target renal epithelial cell migration and apoptosis in diabetic renal embryopathy. [PDF]

PLoS ONE, 2013
Maternal hyperglycemia can inhibit morphogenesis of ureteric bud branching, Glial cell line-derived neurotrophilic factor (GDNF) is a key regulator of the initiation of ureteric branching.
Ching-Yuang Lin, Tze-Yi Lin, Min-Chun Lee, Shih-Chieh Chen, Jeng-Shou Chang   +4 more
doaj   +1 more source

Utilizing One-Way Valve to Optimize Turbocharger Performance on a Blended EGR Engine

Frontiers in Mechanical Engineering, 2021
Internal combustion engines will be a part of personal transportation for the foreseeable future. One recent trend for engines has been downsizing which enables the engine to run more favorably over regulatory drive cycles.
Gaurav Handa, Bradley Denton, Sankar Rengarajan, Christopher Chadwell, Graham Conway   +4 more
doaj   +1 more source

Industrial Structure and Ecological Sustainability: Evidence From Small‐Scale Industries in Nordic Countries

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines how industrial structure is associated with ecological sustainability in Nordic countries over the period 2001–2022. The analysis focuses on the share of small‐scale industries in the industrial system and examines its association with ecological sustainability, measured by the load capacity factor.
Ismail Demirdag, Abdullah Emre Caglar, Mustafa Naimoğlu   +2 more
wiley   +1 more source

Numerical study on effects of EGR on combustion and NOx emissions of gasoline blended dissociated methanol gas engine

Energy Reports, 2023
Exhaust gas recirculation (EGR), which can reduce NOx emissions effectively, has been widely studied in engines, but there are few studies using EGR on gasoline blended dissociated methanol gas (GDM) engines.
Wangbin Liu, Yankun Jiang, Beidong Zhang, Yexin Chen   +3 more
doaj   +1 more source

Multi‐factor coupling effects in hydraulic fracturing of laminated shale: Experimental insights and physics‐informed neural network‐driven optimization

Deep Underground Science and Engineering, EarlyView.
This study establishes a multi‐factor coupling framework for predicting breakdown pressure in laminated shale by integrating experimental hydraulic fracturing tests, physics‐informed neural networks (PINNs), and Sobol sensitivity analysis. It reveals how differential stress, the bedding dip angle, and the injection rate interact to influence fracture ...
Tao Wang, Guoyao Xu, Liyuan Liu, Yao Zhang, Sitao Zhu, Hongyang Chu, Kaikai Zhao   +6 more
wiley   +1 more source

Effects of hybrid metal oxide nanoparticles on the tribological and emission attributes of algae‐derived biofuel in compression ignition engines

Environmental Progress &Sustainable Energy, EarlyView.
Abstract The growing demand for sustainable fuels has accelerated the development of algae‐derived biodiesel for compression‐ignition engines. In this study, Chlorella vulgaris methyl ester (AME) exhibited physicochemical properties comparable to diesel and satisfied ASTM D6751 fuel quality requirements, making it suitable for blending.
T. Jayakumar, A. Kumaravadivel, I. Rahamathullah, J. Arunprasad   +3 more
wiley   +1 more source

Effect of lower rate of exhaust gas recirculation on CI engine characteristics fueled with Prosopis

Journal of Thermal Engineering
The enormous rise in energy demand with the strict emissions regulations has put together in search of the finest alternative fuel that meets the various emission norms of the vehicles made worldwide.
B. MUSTHAFA, B. SARAVANAN, S. Senthur PRABU, Asokan M. A., S. SUJAI   +4 more
doaj   +1 more source

A Numerical Investigation of the Effects of Piston Bowl Geometry and Spray Angle on Combustion, Performance and Emission of a Diesel Engine

Energy Science &Engineering, EarlyView.
A piston bowl's design and spray angle improve air‐fuel mixing, resulting in more complete combustion and higher efficiency. Ansys Forte 2023 R1 a CFD software was used to analyze the effects of five combustion chamber geometries of cylinder, modified re‐entrant, re‐entrant, double‐stepped, and stepped on engine performance, combustion, and emission ...
Md. Nazmul Haque, Abdullah Al Rifat, Tafsirul Hassan, Md. Ifthaker Alam, Mohammad Mehedi Hasan Kazol, Md. Ashraful Islam, Abidur Rahman Adib, Mizanur Rahman   +7 more
wiley   +1 more source

Proline-rich tyrosine kinase 2 mediates gonadotropin-releasing hormone signaling to a specific extracellularly regulated kinase-sensitive transcriptional locus in the luteinizing hormone beta-subunit gene [PDF]

, 2007
G protein-coupled receptor regulation of gene transcription primarily occurs through the phosphorylation of transcription factors by MAPKs. This requires transduction of an activating signal via scaffold proteins that can ultimately determine the outcome
Naor, Zvi, Pawson, Adam J, Maudsley, Stuart, Pope, Caroline, Bonfil, David, Davidson, Lindsay, Brown, Pamela; id_orcid, Larder, Rachel, Millar, Robert P, Karali, Dimitra, Nelson, Nancy   +10 more
core   +1 more source