Results 151 to 160 of about 4,903 (185)

The N-terminal glycine of EHV-1 UL11 is essential for the localization of UL11 and EHV-1 replication in cultured cells

Journal of General Virology, 2023
Equine herpesvirus type 1 (EHV-1) UL11 is a 74-amino-acid (aa) protein encoded by ORF51. UL11 is modified by acylation including myristoylation and palmitoylation. Myristoylation of EHV-1 UL11 is assumed to occur on the N-terminal glycine, while palmitoylation is assumed to occur on the seventh and ninth cysteines. ORF51, which encodes the first 24 aa,
Noriko Fukushi, Yassien Badr, Hideto Fukushi   +2 more
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Equine herpesvirus 1 (EHV-1) glycoprotein D DNA inoculation in horses with pre-existing EHV-1/EHV-4 antibody

Veterinary Microbiology, 2000
We have shown previously that equine herpesvirus 1 (EHV-1) glycoprotein D (gD) DNA elicited protective immune responses against EHV-1 challenge in murine respiratory and abortion models of EHV-1 disease. In this study, 20 horses, all with pre-existing antibody to EHV-4 and two with pre-existing antibody to EHV-1, were inoculated intramuscularly with ...
K M, Ruitenberg, D N, Love, J R, Gilkerson, J E, Wellington, J M, Whalley   +4 more
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Protective effects of equine herpesvirus-1 (EHV-1) glycoprotein B in a murine model of EHV-1-induced abortion

Veterinary Microbiology, 1998
In an attempt to determine if pregnant mice could be protected from abortion subsequent to challenge with equine herpesvirus-1 (EHV-1) in the mouse model of EHV-1 disease, female BALB/c mice were inoculated with baculovirus-expressed EHV-1 glycoprotein B (bac-gB), wild-type baculovirus (bac-wt), rabbit kidney (RK-13) or baby hamster kidney (BHK-21 ...
A, Kukreja, C, Walker, T, Fitzmaurice, A, Awan, D N, Love, J M, Whalley, H J, Field   +6 more
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Fatal Nonneurological EHV-1 Infection in a Yearling Filly

Veterinary Pathology, 2000
A case of fatal nonneurological equine herpesvirus 1 (EHV-1) infection in a yearling filly is described. Gross lesions included extensive pulmonary edema, prominent laryngeal lymphoid follicles, and congestion and edema of the dorsal third ventricle choroid plexus.
F, Del Piero, P A, Wilkins, P J, Timoney, J, Kadushin, H, Vogelbacker, J W, Lee, S J, Berkowitz, K M, La Perle   +7 more
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A murine model for studying EHV-1-induced abortion

Research in Veterinary Science, 1991
Balb/c mice were infected with two abortigenic strains of equine herpesvirus-1 (EHV-1) by intranasal inoculation. The inoculation of one strain produced subclinical disease while the other produced a disease characterised by weight loss, constitutional signs, and death in the most severely affected animals.
A R, Awan, J S, Gibson, H J, Field
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DNA-mediated immunization with glycoprotein D of equine herpesvirus 1 (EHV-1) in a murine model of EHV-1 respiratory infection

Vaccine, 1999
DNA-mediated immunization was assessed in a murine model of equine herpesvirus 1 (EHV-1) respiratory infection. A single intramuscular injection with plasmid DNA encoding EHV-1 glycoprotein D (EHV-1 gD), including its predicted C-terminal membrane anchor sequence, induced a specific antibody response detectable by 2 weeks and maintained through 23 ...
K M, Ruitenberg, C, Walker, J E, Wellington, D N, Love, J M, Whalley   +4 more
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A vectored equine herpesvirus type 1 (EHV-1) vaccine elicits protective immune responses against EHV-1 and H3N8 equine influenza virus

Vaccine, 2010
Vaccination is commonly used to control equine respiratory pathogens such as equine herpesvirus type 1 (EHV-1) and equine influenza virus (EIV). Here, we describe the generation and characterization of a recombinant EHV-1 modified live virus vaccine (MLV) based on a recent abortogenic EHV-1 strain, NY03.
Gerlinde R, Van de Walle, Maeva A, May, Sarah T, Peters, Stephan M, Metzger, Cristina T, Rosas, Nikolaus, Osterrieder   +5 more
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Investigation of the role of mules as silent shedders of EHV‐1 during an outbreak of EHV‐1 myeloencephalopathy in California

Veterinary Record, 2012
EQUINE herpesvirus-1 (EHV-1) is an economically important pathogen affecting horses and exerts its major impact by inducing abortion storms or sporadic abortions in pregnant mares, early neonatal death in foals and respiratory disease in young horses (Ostlund 1993).
N, Pusterla, S, Mapes, C, Wademan, A, White, K, Estell, E, Swain   +5 more
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Equine Herpesvirus Type 1 (EHV‐1) Myeloencephalopathy: a Case Report

Journal of Veterinary Medicine, Series B, 2002
An outbreak of neurological disease occurred in a well‐managed riding school. Ataxia and paresis were observed in several horses, five of which became recumbent and were euthanized. Post‐mortem analysis revealed scattered haemorrhages along the spinal cord, that were reflected by multiple haemorrhagic foci on formalin‐fixed sections, with the thoracic ...
B, Stierstorfer, W, Eichhorn, W, Schmahl, C, Brandmüller, O R, Kaaden, A, Neubauer   +5 more
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Inoculation of mares and very young foals with EHV-1 glycoproteins D and B reduces virus shedding following respiratory challenge with EHV-1

Veterinary Immunology and Immunopathology, 2006
We have previously demonstrated that intramuscular inoculation of EHV-1 glycoprotein D (gD) and glycoprotein B (gB) produced by a recombinant baculovirus and formulated with the adjuvant Iscomatrix elicited virus-neutralizing antibody and gD- and gB-specific ELISA antibody in adult horses.
Foote, C.E., Raidal, S.L., Pecenpetelovska, G., Wellington, J.E., Whalley, J.M.   +4 more
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