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Regulation of HDL dysfunctionality by phosphatidylethanolamine links poly-unsaturated fatty acids with atherosclerotic cardiovascular diseases. [PDF]

open access: yesMol Metab
Taradeh M   +26 more
europepmc   +1 more source
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Fatty acids, eicosanoids and PPAR gamma

European Journal of Pharmacology, 2016
Rachel Marion-Letellier, Subrata Ghosh
exaly   +2 more sources

Role of arachidonic acid-derived eicosanoids in intestinal innate immunity

Critical reviews in food science and nutrition, 2020
Arachidonic acid (ARA), an n-6 essential fatty acid, plays an important role in human and animal growth and development. The ARA presents in the membrane phospholipids can be released by phospholipase A2.
Ningning Huang   +3 more
semanticscholar   +1 more source

Metabolomics revealed decreased level of omega‐3 PUFA‐derived protective eicosanoids in pregnant women with pre‐eclampsia

Clinical and Experimental Pharmacology and Physiology, 2019
Pre‐eclampsia (PE) is considered a leading cause of mortality and morbidity in pregnant women worldwide. Eicosanoids derived from polyunsaturated fatty acids (PUFAs) might play an important role in the occurrence and development of PE.
Yantao Liu   +7 more
semanticscholar   +1 more source

Lung Eicosanoid Metabolism

Clinics in Chest Medicine, 1989
Eicosanoids are metabolites of the essential fatty acid, arachidonic acid, which is an integral part of all cell membranes. Membrane damage (as in lung injury) and stretching of tissues are recognized stimuli for lung prostaglandin release, indicating a spectrum of possible roles of eicosanoids in the function of the normal and diseased lung.
N F, Voelkel   +3 more
openaire   +2 more sources

The Eicosanoids, Redox-Regulated Lipid Mediators in Immunometabolic Disorders

Antioxidants and Redox Signaling, 2017
Significance: The oxidation of arachidonic acid via cyclooxygenase (COX) and lipoxygenase (LOX) activity to produce eicosanoids during inflammation is a well-known biosynthetic pathway.
A. Araújo, C. Wheelock, J. Haeggström
semanticscholar   +1 more source

Eicosanoids and ovulation

Prostaglandins, Leukotrienes and Essential Fatty Acids, 1993
PGs and probably other eicosanoids play a fundamental role in the process of ovulation, more specifically in the mechanism of follicle wall rupture. Although the nature of this role has yet to be established a number of plausible theories exist. It seems likely that altered PG metabolism is responsible for some cases of human female subfertility.
A R, Priddy, S R, Killick
openaire   +2 more sources

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