Mutations in Nonessential eIF3k and eIF3l Genes Confer Lifespan Extension and Enhanced Resistance to ER Stress in Caenorhabditis elegans [PDF]
, 2016 The translation initiation factor eIF3 is a multi-subunit protein complex that coordinates the assembly of the 43S pre-initiation complex in eukaryotes.
Cattie, Douglas John +7 more
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Differential induction of apoptosis, interferon signaling, and phagocytosis in macrophages infected with a panel of attenuated and nonattenuated poxviruses [PDF]
, 2014 Due to the essential role macrophages play in antiviral immunity, it is important to understand the intracellular and molecular processes that occur in macrophages following infection with various strains of vaccinia virus, particularly those used as ...
Guerra, Susana M. +5 more
core +2 more sources
Implications of the use of eukaryotic translation initiation factor 5A (eIF5A) for prognosis and treatment of hepatocellular carcinoma [PDF]
, 2012 published_or_final_versio
Fatima, S, Lee, NPY, Shek, HP
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Disruption of an RNA helicase/RNAse III gene in Arabidopsis causes unregulated cell division in floral meristems [PDF]
, 1999 Arabidopsis thaliana floral meristems are determinate structures that produce a defined number of organs, after which cell division ceases. A new recessive mutant, carpel factory (caf), converts the floral meristems to an indeterminate state.
Jacobsen, Steven E. +2 more
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Indian journal of biochemistry & biophysics, 1995 Mechanism of regulation of eIF-2 alpha-subunit phosphorylation by dsI and p67 was studied. The results are as follows: (1) At low dsI concentration, p67 protected equimolar concentration of eIF-2. (2) At high dsI concentration, dsI efficiently phosphorylated eIF-2 alpha-subunit even when equimolar concentrations of both p67 and eIF-2 were present ...
A, Chakraborty +5 more
openaire +1 more source
The mTOR Pathway in Breast Cancer [PDF]
, 2018 There is currently a wealth of information regarding the mutations that contribute to cancer development. Most of these mutations alter the expression and activity of signal transduction proteins.
Boulay, Anne, Hynes, Nancy
core
Potential Role of Protein Kinase B in Insulin-induced Glucose Transport, Glycogen Synthesis, and Protein Synthesis [PDF]
, 1997 Various biological responses stimulated by insulin have been thought to be regulated by phosphatidylinosi-tol 3-kinase, including glucose transport, glycogen syn-thesis, and protein synthesis.
Akanuma, Y. +10 more
core +1 more source
Cervical cancer screening by enhanced cytology: application of novel markers [PDF]
, 2014 published_or_final_versio
Cheung, ANY, Guan, X, Ngan, HYS
core