Results 121 to 130 of about 147,930 (294)

Interpretable PROTAC Degradation Prediction With Structure‐Informed Deep Ternary Attention Framework

open access: yesAdvanced Science, EarlyView.
PROTAC‐STAN, a structure‐informed deep learning framework is presented for interpretable PROTAC degradation prediction. By modeling molecular hierarchies and protein structures, and simulating ternary interactions via a novel attention network, PROTAC‐STAN achieves significant performance gains over baselines.
Zhenglu Chen   +11 more
wiley   +1 more source

Shear Conditioning Promotes Microvascular Endothelial Barrier Resilience in a Human BBB‐on‐a‐Chip Model of Systemic Inflammation Leading to Astrogliosis

open access: yesAdvanced Science, EarlyView.
Physiological flow (0.5 Pa) conditioning promotes resilience of an iPSC‐derived blood–brain barrier endothelium to mild systemic inflammation. In contrast, high “cytokine storm” levels induce barrier breakdown, fibrinogen leakage, and astrocyte activation, reconstituting the two‐hit injury mechanism on‐a‐chip.
Kaihua Chen   +15 more
wiley   +1 more source

Einstein and the Quantum

open access: yes, 2006
We review here the main contributions of Einstein to the quantum theory. To put them in perspective we first give an account of Physics as it was before him. It is followed by a brief account of the problem of black body radiation which provided the context for Planck to introduce the idea of quantum.
openaire   +3 more sources

Flexible Mechanical Response Device With Optical Logic Emission Enabled by Synergistic Crystallization Engineering of Ester Polymer and Perovskite

open access: yesAdvanced Science, EarlyView.
This study presents a flexible mechanical response device (FMRD) with optical logic properties, developed via synergistic crystallization engineering of ester‐based polymers and perovskite. Ion‐dipole interactions and crystallized space confinement tune perovskite crystal dimensions, enhancing exciton transfer and emission.
Zhen‐Li Yan   +13 more
wiley   +1 more source

Geriatria, Gerontologia E Envelhecimento: Protagonismo Obrigatório [PDF]

open access: yesGeriatrics, Gerontology and Aging
Nenhum.
Einstein F. Camargos
doaj  

Home - About - Disclaimer - Privacy