Results 11 to 20 of about 2,235,192 (340)

The SGLT2 inhibitor dapagliflozin in heart failure with preserved ejection fraction: a multicenter randomized trial

Nature Medicine, 2021
Patients with heart failure and preserved ejection fraction (HFpEF) have a high burden of symptoms and functional limitations, and have a poor quality of life.
M. Nassif, Sheryl L. Windsor, B. Borlaug, D. Kitzman, Sanjiv J. Shah, F. Tang, Yevgeniy Khariton, A. Malik, T. Khumri, G. Umpierrez, S. Lamba, K. Sharma, S. Khan, L. Chandra, R. Gordon, J. Ryan, S. Chaudhry, S. Joseph, C. Chow, M. Kanwar, M. Pursley, Elias S. Siraj, G. Lewis, B. Clemson, Michael W Fong, M. Kosiborod   +25 more
semanticscholar   +1 more source

The correlation of left atrial diameter with preserved ejection fraction, reduced ejection fraction, and mid‐range ejection fraction

Clinical Cardiology, 2023
AbstractBackgroundIn patients with heart failure, left atrial remodeling often occurs to varying degrees. Left atrial enlargement has been proved to be an important predictor of cardiovascular‐related adverse events. However, the relationship between left atrial diameter (LAD) with heart failure (HF) with preserved ejection fraction (HFpEF), reduced ...
Jing Lin, Huajui Wu, Tianwen Zhang
openaire   +2 more sources

Heart failure with mildly reduced ejection fraction: retrospective study of ejection fraction trajectory risk

ESC Heart Failure, 2022
Aims Heart failure with mildly reduced ejection fraction (HFmrEF) is associated with a favourable prognosis compared with heart failure (HF) with reduced ejection fraction (EF). We assessed whether left ventricular ejection fraction (LVEF) trajectory can
Robert J.H. Miller, Majid Nabipoor, Erik Youngson, Gynter Kotrri, Nowell M. Fine, Jonathan G. Howlett, Ian D. Paterson, Justin Ezekowitz, Finlay A. McAlister   +8 more
doaj   +1 more source

Myocardial Metabolomics of Human Heart Failure With Preserved Ejection Fraction

Circulation, 2023
Background: The human heart primarily metabolizes fatty acids, and this decreases as alternative fuel use rises in heart failure with reduced ejection fraction (HFrEF).
V. Hahn, Christopher Petucci, Min-Soo Kim, K. Bedi, Hanghang Wang, Sumita Mishra, N. Koleini, Edwin J. Yoo, K. Margulies, Z. Arany, D. Kelly, D. Kass, K. Sharma   +12 more
semanticscholar   +1 more source

Heart failure with preserved ejection fraction [PDF]

Pflügers Archiv - European Journal of Physiology, 2014
Heart failure (HF) is a clinical syndrome of diverse etiologies and can be associated with preserved, reduced, or mid-range ejection fraction (EF). In the community, heart failure with preserved ejection fraction (HFpEF) is emerging as the most common form of HF.
James D, Gladden, Antoine H, Chaanine, Margaret M, Redfield   +2 more
openaire   +6 more sources

Heart failure with mid-range or mildly reduced ejection fraction

Nature Reviews Cardiology, 2021
Left ventricular ejection fraction (EF) remains the major parameter for diagnosis, phenotyping, prognosis and treatment decisions in heart failure. The 2016 ESC heart failure guidelines introduced a third EF category for an EF of 40–49%, defined as heart
G. Savarese, D. Stolfo, G. Sinagra, L. Lund   +3 more
semanticscholar   +1 more source

The Role of Cardiac Imaging in Heart Failure with Reduced Ejection Fraction

Cardiac Failure Review, 2022
Heart failure (HF) is a major health burden associated with significant morbidity and mortality. Approximately half of all HF patients have reduced ejection fraction (left ventricular ejection fraction
Rebecca C Gosling, Abdallah Al-Mohammad
doaj   +1 more source

Diabetes Associated With Greater Ejection Fraction Improvement After Revascularization in Patients With Reduced Ejection Fraction

Frontiers in Cardiovascular Medicine, 2021
Objectives: To investigate the association between diabetes mellitus (DM) and ejection fraction (EF) improvement following revascularization in patients with coronary artery disease (CAD) and left ventricular (LV) dysfunction.Background ...
Shaoping Wang, Shaoping Wang, Bijan J. Borah, Bijan J. Borah, Shujuan Cheng, Shiying Li, Ze Zheng, Xiaoyan Gu, Ming Gong, Yi Lyu, Jinghua Liu   +10 more
doaj   +1 more source

Heart failure with mildly reduced ejection fraction: emerging frontiers in clinical characteristics, prognosis, and treatment [PDF]

Reviews in Cardiovascular Medicine, 2022
Heart failure (HF) is a complex clinical syndrome resulting from the impairment of ventricular filling or ejection of blood or both, leading to considerable morbidity and mortality. Based on left ventricular ejection fraction (LVEF), the 2016 European
Zhi Shang, Xinyu Wang, Wei Gao
doaj   +1 more source

Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction.

New England Journal of Medicine, 2019
BACKGROUND In patients with type 2 diabetes, inhibitors of sodium-glucose cotransporter 2 (SGLT2) reduce the risk of a first hospitalization for heart failure, possibly through glucose-independent mechanisms. More data are needed regarding the effects of
J. McMurray, S. Solomon, S. Inzucchi, L. Køber, M. Kosiborod, F. Martinez, P. Ponikowski, M. Sabatine, I. Anand, J. Bělohlávek, M. Böhm, C. Chiang, V. Chopra, Rudolf A. de Boer, Akshay S. Desai, M. Diez, J. Drożdż, A. Dukát, J. Ge, J. Howlett, T. Katova, M. Kitakaze, C. Ljungman, B. Merkely, J. Nicolau, E. O’Meara, M. Petrie, P. N. Vinh, M. Schou, S. Tereshchenko, S. Verma, C. Held, D. DeMets, K. Docherty, P. Jhund, O. Bengtsson, M. Sjöstrand, A. Langkilde, Modele O Ogunniyi   +38 more
semanticscholar   +1 more source