Results 231 to 240 of about 2,235,192 (340)

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source

Immunology of heart failure with preserved ejection fraction. [PDF]

Expert Rev Clin Immunol
Wang B, Jankauskas SS, Mone P, Varzideh F, Santulli G.   +4 more
europepmc   +1 more source

Microgel‐Based Hierarchical Porous Hydrogel Patch with Adhesion and Resilience for Myocardial Infarction

Advanced Science, EarlyView.
This study develops a hierarchically porous hydrogel patch strategy (HPMP), based on gas‐shearing microfluidics and an aqueous two‐phase system to fabricate porous microgels as microgel‐based bioinks. The porous microgels with controllable porous structure exhibit excellent cellular behavior.
Ziyang Liu, Leyan Xuan, Yingying Hou, Ting Xie, Jieting Li, Junjie Cai, Siyu Zhang, Yingling Miao, Ning Hou, Gen He, Maobin Xie, Xiyong Yu, Mingen Xu, Guosheng Tang   +13 more
wiley   +1 more source

Patient-Reported Health Status Among Patients With Heart Failure With Improved Ejection Fraction. [PDF]

J Am Heart Assoc
Vasti E, Zheng J, Kalwani NM, DeJong C, Bhatt AS, Ambrosy AP, Din N, Nallamshetty S, Sallam K, Heidenreich P, Sandhu AT.   +10 more
europepmc   +1 more source

Heart Failure with preserved Ejection Fraction (HFpEF); A Mexican cohort from Mexican Institute of Social Security (IMSS) [PDF]

, 2019
Peralta MR, Martin Rosas Peralta, Daniela Salinas Morales, Alejandro Chanona Espinosa, Alicia Contreras Rodríguez, Erick Ramírez Arias, Carlos Riera Kinkel, Guadalupe Castro Martínez, José Antonio Magaña-Serrano   +8 more
openalex   +1 more source

Moderately Abnormal Ejection Fraction [PDF]

, 2020
openaire   +1 more source

First-Phase Ejection Fraction

JACC: Cardiovascular Imaging, 2019
Jordi S. Dahl, Rasmus Carter-Storch
openaire   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

Frailty Status Predicts Adverse Outcomes in Ambulatory Heart Failure With Preserved Ejection Fraction. [PDF]

JACC Adv
Tanacli R, Trivedi RK, Tajdini M, Jani V, Tian J, Hahn VS, Vaishnav J, Damluji AA, Gerstenblith G, Buta B, Xue QL, Sharma K.   +11 more
europepmc   +1 more source

Prognostic Value of Ejection Fraction in Patients Admitted with Non-ST-Segment Elevatin Myocardial Infarction [PDF]

, 2019
Veronica Gheorman, Venera Cristina Dinescu, Michael Schenker, Denise Ramona Malin, Mioara Desdemona Stepan, Oana Criciotoiu, Diana Stanca, Adrian Mită, Sorin Nicolae Dinescu, Elena Cătălina Bică, Marius Bică, Manuela Dragomir, Florin Marius Romanescu, Razvan Cosmin Pana, Victor Gheorman   +14 more
openalex   +1 more source