Results 21 to 30 of about 2,235,192 (340)

Dapagliflozin across the range of ejection fraction in patients with heart failure: a patient-level, pooled meta-analysis of DAPA-HF and DELIVER

Nature Medicine, 2022
Whether the sodium–glucose cotransporter 2 inhibitor dapagliflozin reduces the risk of a range of morbidity and mortality outcomes in patients with heart failure regardless of ejection fraction is unknown.
P. Jhund, T. Kondo, J. Butt, K. Docherty, B. Claggett, Akshay S. Desai, M. Vaduganathan, S. Gasparyan, O. Bengtsson, D. Lindholm, Magnus Petersson, A. Langkilde, R. D. de Boer, D. DeMets, A. Hernandez, S. Inzucchi, M. Kosiborod, L. Køber, C. Lam, F. Martinez, M. Sabatine, Sanjiv J. Shah, S. Solomon, J. McMurray   +23 more
semanticscholar   +1 more source

Heart Failure with Preserved Ejection Fraction [PDF]

New England Journal of Medicine, 2016
Heart failure with preserved ejection fraction and sex differences.
Jonathan R, Dalzell, Kirsty M, McDowell
  +11 more sources

Late ventricular potentials in risk assessment of the occurrence of complex ventricular arrhythmia in patients with myocardial infarction and heart failure [PDF]

Vojnosanitetski Pregled, 2004
Aim. To determine the prognostic significance of late ventricular potentials on signal-averaged electrocardiogram and left ventricular ejection fraction for the occurrence of complex ventricular arrhythmia in patients treated with accelerated tissue-type
Ćosić Zoran, Tavčiovski Dragan, Jovelić Aleksandra, Romanović Radoslav   +3 more
doaj   +1 more source

Patiromer for the management of hyperkalemia in heart failure with reduced ejection fraction: the DIAMOND trial

European Heart Journal, 2022
Aims To investigate the impact of patiromer on the serum potassium level and its ability to enable specified target doses of renin–angiotensin–aldosterone system inhibitor (RAASi) use in patients with heart failure and reduced ejection fraction (HFrEF ...
J. Butler, S. Anker, L. Lund, A. Coats, G. Filippatos, T. Siddiqi, T. Friede, V. Fabien, M. Kosiborod, M. Metra, I. Piña, F. Pinto, P. Rossignol, P. van der Meer, Cecilia Bahit, J. Bělohlávek, M. Böhm, J. Brugts, J. Cleland, J. Ezekowitz, A. Bayés‐Genís, I. Gotsman, A. Goudev, I. Khintibidze, J. Lindenfeld, R. Mentz, B. Merkely, Eliodoro Castro Montes, W. Mullens, J. Nicolau, A. Parkhomenko, P. Ponikowski, P. Seferovic, M. Senni, E. Shlyakhto, A. Cohen-Solal, P. Szecsödy, K. Jensen, F. Dorigotti, M. Weir, B. Pitt   +40 more
semanticscholar   +1 more source

Diabetes Mellitus and Heart Failure With Preserved Ejection Fraction: Role of Obesity

Frontiers in Physiology, 2022
Heart failure with preserved ejection fraction is a growing epidemic and accounts for half of all patients with heart failure. Increasing prevalence, morbidity, and clinical inertia have spurred a rethinking of the pathophysiology of heart failure with ...
Aneesh Dhore-patil, Aneesh Dhore-patil, Tariq Thannoun, Tariq Thannoun, Rohan Samson, Rohan Samson, Thierry H. Le Jemtel, Thierry H. Le Jemtel   +7 more
doaj   +1 more source

Baseline Characteristics of Patients With HF With Mildly Reduced and Preserved Ejection Fraction: DELIVER Trial.

JACC. Heart failure, 2022
OBJECTIVES This report describes the baseline clinical profiles and management of DELIVER (Dapagliflozin Evaluation to Improve the Lives of Patients With Preserved Ejection Fraction Heart Failure) trial participants and how these compare with those in ...
S. Solomon, M. Vaduganathan, B. Claggett, Rudolf A. de Boer, D. DeMets, Adrian F. Hernandez, S. Inzucchi, M. Kosiborod, C. Lam, F. Martinez, Sanjiv J. Shah, J. Bělohlávek, C. Chiang, C. J. Willem Borleffs, J. Comín-Colet, D. Dobreanu, J. Drożdż, J. Fang, M. Alcocer Gamba, Waleed Al habeeb, Yaling Han, Jose Walter Cabrera Honorio, S. Janssens, T. Katova, M. Kitakaze, B. Merkely, E. O’Meara, J. K. Kerr Saraiva, S. Tereschenko, J. Thierer, O. Vardeny, S. Verma, P. N. Vinh, U. Wilderäng, Natalia Zaozerska, D. Lindholm, Magnus Petersson, J. McMurray   +37 more
semanticscholar   +1 more source

Heart failure with preserved ejection fraction: recent concepts in diagnosis, mechanisms and management

Heart, 2022
It is estimated that half of all patients with heart failure (HF) have HF with preserved ejection fraction (HFpEF). Yet this form of HF remains a diagnostic and therapeutic challenge.
A. Gevaert, Rachna Kataria, F. Zannad, Andrew J. Sauer, K. Damman, K. Sharma, Sanjiv J. Shah, H. V. Van Spall   +7 more
semanticscholar   +1 more source

Factors influencing left ventricular ejection fraction in patients with coronary microvascular disease and obstructive coronary artery disease

BMC Research Notes, 2020
Objective The aim of our research was to evaluate the relationship involving left ventricular ejection fraction, low density lipoprotein, B-type natriuretic peptide, Troponin I and coronary flow reserve, and to determine the predictors of left ...
Henry Anselmo Mayala, Magesa Mafuru, Abdalah Mkangala, Mark Mayala, Pedro Pallangyo, Dickson Minja, Mohamed Janabi, Wang Zhao-hui   +7 more
doaj   +1 more source

Sacubitril/valsartan in patients with mildly reduced or preserved ejection fraction and worsening heart failure: A review

Терапевтический архив, 2023
Heart failure with mildly reduced ejection fraction and heart failure with preserved ejection fraction are associated with significant morbidity and mortality, as well as growing economic burden.
Igor V. Zhirov, Natalia V. Safronova, Sergey N. Tereshchenko   +2 more
doaj   +1 more source

Dapagliflozin in heart failure with preserved and mildly reduced ejection fraction: rationale and design of the DELIVER trial

European Journal of Heart Failure, 2021
Sodium–glucose co‐transporter 2 (SGLT2) inhibitors, originally developed as glucose‐lowering agents, have been shown to reduce heart failure hospitalizations in patients with type 2 diabetes without established heart failure, and in patients with heart ...
S. Solomon, Rudolf A. de Boer, D. DeMets, Adrian F. Hernandez, S. Inzucchi, M. Kosiborod, C. Lam, F. Martinez, Sanjiv J. Shah, D. Lindholm, U. Wilderäng, F. Öhrn, B. Claggett, A. Langkilde, Magnus Petersson, J. McMurray   +15 more
semanticscholar   +1 more source