Results 41 to 50 of about 2,235,192 (340)

Phenotyping Heart Failure According to the Longitudinal Ejection Fraction Change: Myocardial Strain, Predictors, and Outcomes

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Many patients with heart failure (HF) experience changes in left ventricular ejection fraction (LVEF) during follow‐up. We sought to evaluate the predictors and outcomes of different HF phenotypes according to longitudinal changes in EF ...
Jin Joo Park   +5 more
doaj   +1 more source

How to diagnose heart failure with preserved ejection fraction: the HFA-PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC).

open access: yesEuropean Heart Journal, 2019
Making a firm diagnosis of chronic heart failure with preserved ejection fraction (HFpEF) remains a challenge. We recommend a new stepwise diagnostic process, the 'HFA-PEFF diagnostic algorithm'.
B. Pieske   +23 more
semanticscholar   +1 more source

Surgical myocardial revascularization of patients with ischemic cardiomyopathy and severe left ventricular disfunction

open access: yesClinics, 2010
OBJECTIVE: To determine long-term survival, identify preoperative factors predictive of a favorable outcome, and assess functional improvement after coronary artery bypass grafting in patients with advanced left ventricular dysfunction.
André L. Hovnanian   +6 more
doaj   +1 more source

SGLT2 inhibitors in patients with heart failure with reduced ejection fraction: a meta-analysis of the EMPEROR-Reduced and DAPA-HF trials.

open access: yesThe Lancet, 2020
BACKGROUND Both DAPA-HF (assessing dapagliflozin) and EMPEROR-Reduced (assessing empagliflozin) trials showed that sodium-glucose co-transporter-2 (SGLT2) inhibition reduced the combined risk of cardiovascular death or hospitalisation for heart failure ...
F. Zannad   +10 more
semanticscholar   +1 more source

Nicotinamide for the treatment of heart failure with preserved ejection fraction

open access: yesScience Translational Medicine, 2021
The NAD+ precursor nicotinamide improves diastolic dysfunction caused by aging, hypertension, or metabolic syndrome in rodents. Diet and diastolic dysfunction Increasing nicotinamide adenine dinucleotide (NAD+) can mimic some of the benefits of caloric ...
M. Abdellatif   +43 more
semanticscholar   +1 more source

The Prognostic Role of the Left Atrium in Hypertensive Patients with HFpEF: Does Function Matter More than Structure?

open access: yesLife
Background: In arterial hypertension (AH), adverse hemodynamic consequences in the left atrium (LA) are often observed. The prognostic significance of functional vs.
Artem Ovchinnikov   +6 more
doaj   +1 more source

A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation.

open access: yesJournal of the American College of Cardiology, 2013
Over the past decade, myocardial structure, cardiomyocyte function, and intramyocardial signaling were shown to be specifically altered in heart failure with preserved ejection fraction (HFPEF). A new paradigm for HFPEF development is therefore proposed,
W. Paulus, C. Tschöpe
semanticscholar   +1 more source

Prevalence of Transthyretin Amyloid Cardiomyopathy in Heart Failure With Preserved Ejection Fraction.

open access: yesJAMA cardiology, 2021
Importance Heart failure (HF) with preserved ejection fraction (HFpEF) is common, is frequently associated with ventricular wall thickening, and has no effective therapy.
O. AbouEzzeddine   +14 more
semanticscholar   +1 more source

Heart Failure with Reduced Ejection Fraction: The Role of Cardiovascular and Lung Ultrasound beyond Ejection Fraction

open access: yesDiagnostics, 2023
Heart failure with reduced ejection fraction (HFrEF) is considered a major health care problem with frequent decompensations, high hospitalization and mortality rates.
Syuzanna Shahnazaryan   +2 more
doaj   +1 more source

Effect of Empagliflozin on Worsening Heart Failure Events in Patients With Heart Failure and Preserved Ejection Fraction

open access: yesCirculation, 2021
Supplemental Digital Content is available in the text. Background: Empagliflozin reduces the risk of cardiovascular death or hospitalization for heart failure in patients with heart failure with preserved ejection fraction, but additional data are needed
M. Packer   +17 more
semanticscholar   +1 more source

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