Results 101 to 110 of about 111,358 (307)

Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B12 analog. [PDF]

open access: yes, 2019
People heterozygous for an activating mutation in protein kinase G1 (PRKG1, p.Arg177Gln) develop thoracic aortic aneurysms and dissections (TAAD) as young adults.
Boss, Gerry R   +15 more
core   +1 more source

Drug treatment of hypertension: focus on vascular health [PDF]

open access: yes, 2016
Hypertension, the most common preventable risk factor for cardiovascular disease and death, is a growing health burden. Serious cardiovascular complications result from target organ damage including cerebrovascular disease, heart failure, ischaemic heart
Cameron, Alan C.   +2 more
core   +1 more source

Bone Organoids: A Novel Tool for Modeling and Managing Skeletal Disorders in Diabetes

open access: yesAdvanced Science, EarlyView.
This review synthesizes advances in bone organoid engineering and evaluates their potential to model diabetic bone fragility. Current in vitro and animal models do not fully recapitulate diabetes‐associated skeletal phenotypes. Cell‐based and scaffold‐based bone organoids are discussed as complementary approaches to reconstruct multicellular bone ...
Shuangzhe Lin   +2 more
wiley   +1 more source

Characterization of Novel Hybrid Materials Conditioned as Sheets for Skin Repair

open access: yesProceedings, 2019
The association of natural or synthetic polymers with metal nanoparticles resulted in hybrid [...]
Daniela Ilie   +6 more
doaj   +1 more source

Guided Tissue Regeneration in Heart Valve Replacement: From Preclinical Research to First-in-Human Trials [PDF]

open access: yes, 2015
Heart valve tissue-guided regeneration aims to offer a functional and viable alternative to current prosthetic replacements. Not requiring previous cell seeding and conditioning in bioreactors, such exceptional tissue engineering approach is a very ...
Gerosa, Gino, Iop, Laura
core   +4 more sources

Approaching Scarless Wound Healing: From Passive Anti‐Fibrotic to Proactive and Programmable Pro‐Regenerative Strategies

open access: yesAdvanced Science, EarlyView.
This review outlines the wound healing process and factors influencing scar formation, explores how certain animals and human fetuses achieve scarless skin or tissue regeneration, and details tissue engineering material strategies employed in scarless wound dressings.
Meimei Fu   +7 more
wiley   +1 more source

Mechanical identification of layer-specific properties of mouse carotid arteries using 3D-DIC and a hyperelastic anisotropic constitutive model [PDF]

open access: yes, 2011
The role of mechanics is known to be of primary order in many arterial diseases; however, determining mechanical properties of arteries remains a challenge.
Finlay HM   +8 more
core   +7 more sources

Bioinspired Cold‐Laminated Ultrathin Hydrogels as a Broadly Adaptive Platform for Physiological Monitoring

open access: yesAdvanced Science, EarlyView.
A cold‐lamination strategy is introduced to fabricate ultrathin, nanomesh‐reinforced hydrogel bioelectronics with controlled thickness, tunable mechanics, and reversible adhesion. By mechanically interlocking a TPU nanomesh within a temperature‐responsive hydrogel, the platform enables robust epidermal and implantable cardiac interfaces, supporting ...
Hui Chen   +10 more
wiley   +1 more source

Control of Elastin Synthesis

open access: yesJournal of Investigative Dermatology, 1982
mRNA was isolated from the thoracic aortas of 16-day chick embryos and used to synthesize blunt-ended heteroduplex molecules consisting of one strand of mRNA and one of cDNA using AMV reverse transcriptase and S1 nuclease. The duplexes were tailed with dCTP and hybridized to the plasmid pBR322 which had been restricted with Pst I and tailed with dGTP ...
Burnett, William   +3 more
openaire   +2 more sources

Seeing Elastin: A Near-Infrared Zwitterionic Fluorescent Probe for In Vivo Elastin Imaging [PDF]

open access: yes, 2018
Elastic fibers are present in a variety of tissues and are responsible for their resilience. Until now, no optical contrast agent in the near-infrared (NIR) wavelength range of 700-900 nm has been reported for the imaging of elastic fibers.
Bae, Myung Ae   +13 more
core   +1 more source

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