Results 101 to 110 of about 345,892 (194)
The FEBS Journal, EarlyView.Sclerostin (SOST) is a multifunctional extracellular modulator of BMP and Wnt signaling. SOST binds with high affinity to fibrillin‐1 and fibrillin‐2, localizing it to fibrillin microfibrils and regulating its extracellular bioavailability. Fibrillin‐bound SOST cannot engage BMP‐7 prodomain (PD) complexes, revealing a competitive mechanism that ...
Annkatrin Correns +11 more
wiley +1 more source
The harnessing potential of carboxymethyl beta glucan: A driver of skin repair
International Journal of Cosmetic Science, EarlyView.Carboxymethyl Beta‐Glucan (CM‐BG) drives skin repair through multifaceted actions, notably in wounded 3D models. It activates Dectin‐1 and mitigates inflammation (reducing pro‐inflammatory mediators, boosting anti‐inflammatory IL‐10) in cellular models, while enhancing epidermal differentiation and collagen I synthesis by fibroblasts across cellular ...
Caroline Pichon +4 more
wiley +1 more source
Self-Assembling VHH-Elastin-Like Peptides for Photodynamic Nanomedicine
, 2017 Recombinant llama heavy-chain antibody fragments (VHHs) are promising tools in the field of targeted nanomedicine. 7D12, a VHH against the epidermal growth factor receptor (EGFR) that is overexpressed in various cancers, has been evaluated as an ...
Jan Pille (1459702) +3 more
core +1 more source
Molecular Oral Microbiology, EarlyView.Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin +6 more
wiley +1 more source
299313The vascular wall is a composite environment made of a myriad of different cell types and a complex extracellular matrix (ECM). The latter has a direct impact on vessel function and pathophysiological remodeling of ECM is associated with ...
Jaisson, Stéphane +11 more
core +1 more source
Design and Immunogenicity of a Nanoparticle Combination Vaccine for Salmonella in Poultry
Plant Biotechnology Journal, EarlyView.ABSTRACT Salmonella enterica serovars (Salmonella) are common causes of bacterial gastroenteritis (salmonellosis) often associated with the consumption of poultry products. The control of Salmonella in broiler chickens is difficult because colonized birds may carry this pathogen undetected into the slaughterhouse and cause meat contamination.
Shabnam Shamriz +6 more
wiley +1 more source
Ideal soft tissue graft in periodontal and peri‐implant applications: A scoping review
Periodontology 2000, EarlyView.Abstract Soft tissue grafts (STG) are used in a wide range of clinical situations including volume augmentation, keratinized tissue increase, and recession coverage around teeth and implants. Each STG, produced from different sources and processed with various techniques, possesses unique material properties and interaction with the host tissues, which
Madeline Yon +4 more
wiley +1 more source
Understanding extracellular vesicles in antiaging
Periodontology 2000, EarlyView.Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad +3 more
wiley +1 more source
Identification of elastin peptides with vasorelaxant activity on rat thoracic aorta
, 1998 Elastin peptides obtained in vivo from the enzymatic degradation of elastic fibers are present in the circulating human blood. In order to verify the role that these peptides may have in the regulation of the vascular tone, the activity of several ...
E. DANIELE +4 more
core +1 more source