Results 221 to 230 of about 49,612 (306)
Endogenous GLP‐1 and exogenous GLP‐1 RAs activate GLP‐1R‐expressing vagal afferents in the portal vein, projecting to the nucleus tractus solitarius (NTS). This input engages brainstem–hypothalamic circuits that regulate metabolic homeostasis. Hypothalamic efferent vagal output to the liver suppresses lipogenesis, enhances triglyceride export, and ...
Gabriel Amorim Moreira Alves +8 more
wiley +1 more source
Traditionally, clinical outcomes measuring how a patient feels, functions, or survives are preferred endpoints in clinical trials; however, some may take a long time to manifest in slowly developing diseases. Biomarkers, if properly validated, can serve as surrogate endpoints, acting as substitutes for clinical outcomes.
Renske Johanna Grupstra +4 more
wiley +1 more source
This cross‐sectional study included adults with MAFLD. Logistic regression and smooth curve fitting were used to evaluate the association between dietary and supplemental niacin intake (mg/day) and depression (PHQ‐9 score ≥ 10). The results indicate that moderate niacin intake may reduce the risk of depression in individuals with MAFLD, with a ...
Xiaoxian Yang +3 more
wiley +1 more source
Evaluation of diagnostic accuracy and molecular adequacy between conventional endobronchial ultrasound, contrast-enhanced endobronchial ultrasound and elastography for hilar and mediastinal lymphadenopathies: a retrospective observational study. [PDF]
Frasca L +4 more
europepmc +1 more source
Gravitational 3D Magnetic Resonance Elastography for Differentiating Focal Nodular Hyperplasia and Hepatic Adenoma. [PDF]
Gruenewald LD +21 more
europepmc +1 more source
Prevalence of Steatotic Liver Disease with Fibrosis and Diagnostic Screening Tools in Patients with Psoriasis. [PDF]
Näslund-Koch C +8 more
europepmc +1 more source

