Results 221 to 230 of about 49,612 (306)

GLP‐1 Receptor Agonists in Metabolic Dysfunction‐Associated Steatotic Liver Disease: Bridging Hepatic and Cardiovascular Outcomes

open access: yesChronic Diseases and Translational Medicine, Volume 12, Issue 2, Page 85-99, June 2026.
Endogenous GLP‐1 and exogenous GLP‐1 RAs activate GLP‐1R‐expressing vagal afferents in the portal vein, projecting to the nucleus tractus solitarius (NTS). This input engages brainstem–hypothalamic circuits that regulate metabolic homeostasis. Hypothalamic efferent vagal output to the liver suppresses lipogenesis, enhances triglyceride export, and ...
Gabriel Amorim Moreira Alves   +8 more
wiley   +1 more source

More Than a Question of Correlation: Characterization of the Evidentiary Basis for Biomarker Surrogates Used in European Marketing Authorizations

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1522-1536, June 2026.
Traditionally, clinical outcomes measuring how a patient feels, functions, or survives are preferred endpoints in clinical trials; however, some may take a long time to manifest in slowly developing diseases. Biomarkers, if properly validated, can serve as surrogate endpoints, acting as substitutes for clinical outcomes.
Renske Johanna Grupstra   +4 more
wiley   +1 more source

Inverse Association Between Dietary Niacin Intake and Prevalence of Depressive Symptoms in Adults With Metabolic‐Associated Fatty Liver Disease: A Cross‐Sectional Study

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
This cross‐sectional study included adults with MAFLD. Logistic regression and smooth curve fitting were used to evaluate the association between dietary and supplemental niacin intake (mg/day) and depression (PHQ‐9 score ≥ 10). The results indicate that moderate niacin intake may reduce the risk of depression in individuals with MAFLD, with a ...
Xiaoxian Yang   +3 more
wiley   +1 more source

Elastography

open access: yes, 2013
Ayush Goel   +2 more
openaire   +1 more source

Elastography a practical approach

open access: yes, 2017
Barr, Richard G.
core  

Gravitational 3D Magnetic Resonance Elastography for Differentiating Focal Nodular Hyperplasia and Hepatic Adenoma. [PDF]

open access: yesDiagnostics (Basel)
Gruenewald LD   +21 more
europepmc   +1 more source

Prevalence of Steatotic Liver Disease with Fibrosis and Diagnostic Screening Tools in Patients with Psoriasis. [PDF]

open access: yesActa Derm Venereol
Näslund-Koch C   +8 more
europepmc   +1 more source

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