Results 211 to 220 of about 70,999 (292)

Identification of Hepatic Fibrosis and Steatosis via A Point‐of‐Care Transient Elastography System With Integrated AI

Liver International, Volume 46, Issue 5, May 2026.
ABSTRACT Background & Aims Transient elastography (TE) is routinely undertaken for non‐invasive assessment of liver fibrosis and steatosis, but is limited by its bulky design, inadequate imaging guidance and conventional algorithmic framework. Thus, we report a real‐time B‐mode image–guided, artificial intelligence–assisted, point‐of‐care TE (AI‐POC‐TE)
Zi‐Hao Huang, Chen‐Hui Ye, Chong‐Lin Wu, Wan‐Rui Li, Miao‐Qin Deng, Li‐You Lian, Chen‐Xiao Huang, Yi‐Xuan Wei, Ying‐Ying Cao, Xiao‐Na Shen, Yi‐Wei Lin, Sui‐Dan Chen, Wai‐Kay Seto, Yong‐Ping Zheng, Ming‐Hua Zheng   +14 more
wiley   +1 more source

Advances in ultrasound for preoperative molecular subtyping of malignant breast tumors. [PDF]

Front Oncol
Hong DR, Huang CY.
europepmc   +1 more source

The MASLD Journey in the General Population: Linkage‐to‐Care and Patient‐Reported Uptake of Fibrosis Risk Assessment

Liver International, Volume 46, Issue 5, May 2026.
ABSTRACT Background & Aims Despite the growing burden of steatotic liver disease (SLD), real‐world evidence on patient‐reported post‐diagnostic care pathways and fibrosis risk assessment remains limited. We aimed to describe the patient‐reported care pathway from initial diagnosis to subsequent follow‐up and fibrosis assessment among individuals with ...
Joo Hyun Oh, Jun‐Hyuk Lee, Sang Bong Ahn, Eunjoo Kwon, Eileen L. Yoon, Hyo Young Lee, Seon Cho, Dae Won Jun   +7 more
wiley   +1 more source

Application of Transthoracic and Endobronchial Elastography-A Systematic Review. [PDF]

Cancers (Basel)
Kildegaard C, Nielsen RW, Laursen CB, Nielsen AD, Juul AD, An TJ, Addala D, Falster C.   +7 more
europepmc   +1 more source

Investigating the performance of shear wave elastography for cardiac stiffness assessment through finite element simulations [PDF]

, 2016
Caenen, Annette, Pernot, Mathieu, Segers, Patrick, Shcherbakova, Darya, Swillens, Abigail, Verdonck, Pascal   +5 more
core  

Cancer‐Associated Fibroblasts Functions as Multifunctional Architects of the Tumor Stroma and Represent Emerging Therapeutic Vulnerabilities

Advanced Science, Volume 13, Issue 24, 27 April 2026.
ABSTRACT Cancer‐associated fibroblasts (CAFs) are the predominant stromal components within the tumor microenvironment (TME), playing multifaceted roles in cancer progression through dynamic interactions with neoplastic and immune cells. Emerging evidence has revealed remarkable heterogeneity and plasticity of CAFs, which originate from diverse ...
Rujiao Liu, Lili Su, Shuiping Gao, Wenting Liu, Hongxia Wang   +4 more
wiley   +1 more source

The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis

Advanced Science, Volume 13, Issue 20, 9 April 2026.
SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo, Yalin Wang, Binyu Lu, Yu Zhang, David M. Frazer, Bing Zhou   +5 more
wiley   +1 more source

Metabolic dysfunction-associated steatotic liver disease, biomarkers, and cardiovascular risk factors in children with excess weight. [PDF]

J Pediatr (Rio J)
Machado EA, Themistocles BLC, Teixeira JMR, Jannuzzi FMG, Tomaz G, Oliveira CL, Madeira IR, Terra C, Souza MDGC, Monteiro A, Bouskela E, Marsillac ME, Collett-Solberg PF.   +12 more
europepmc   +1 more source

AI‐Enhanced Vibrational Capsule for Minimally Invasive Detection of Abnormal Bowel Tissue

Advanced Science, Volume 13, Issue 23, 23 April 2026.
A fully integrated vibration‐assisted capsule is presented for the minimally invasive detection of bowel lesions. The capsule incorporates a wireless sensor and an eccentric motor to probe tissue mechanics in situ. By coupling triaxial vibration signals with AI‐based classification and analytical modeling, the system enables early, non‐visual ...
Xizheng Fang, Yao Yan, Kenneth Omokhagbo Afebu, Andrew Bickerdike, Bo Tian, Yang Liu, Shyam Prasad   +6 more
wiley   +1 more source

Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction

Advanced Science, Volume 13, Issue 19, 2 April 2026.
Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma, Ning Xie, Ziwei Wang, Xiru Liang, Yulong Han, Qiang Zhao, Ming Wang, Hongwei Lu, Wanyi Kou, William Alazawi, Jinhai Wang, Lu Li, Ning Liu, Na Liu, Haitao Shi, Feng Xu   +15 more
wiley   +1 more source